Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection

Here, using longitudinal pre- and post-infection samples from the RV217 Early Capture HIV Cohort Study, the authors show that mucosa-associated invariant T (MAIT) cells become activated and expand during the early acute phase of HIV infection, with subsequent reprogramming towards innate-like functi...

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Autores principales:	Kerri G. Lal, Dohoon Kim, Margaret C. Costanzo, Matthew Creegan, Edwin Leeansyah, Joana Dias, Dominic Paquin-Proulx, Leigh Anne Eller, Alexandra Schuetz, Yuwadee Phuang-ngern, Shelly J. Krebs, Bonnie M. Slike, Hannah Kibuuka, Lucas Maganga, Sorachai Nitayaphan, Josphat Kosgei, Carlo Sacdalan, Jintanat Ananworanich, Diane L. Bolton, Nelson L. Michael, Barbara L. Shacklett, Merlin L. Robb, Michael A. Eller, Johan K. Sandberg
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bd358f6fc61c41148394e312726032c9
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spelling	oai:doaj.org-article:bd358f6fc61c41148394e312726032c92021-12-02T15:37:19ZDynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection10.1038/s41467-019-13975-92041-1723https://doaj.org/article/bd358f6fc61c41148394e312726032c92020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13975-9https://doaj.org/toc/2041-1723Here, using longitudinal pre- and post-infection samples from the RV217 Early Capture HIV Cohort Study, the authors show that mucosa-associated invariant T (MAIT) cells become activated and expand during the early acute phase of HIV infection, with subsequent reprogramming towards innate-like functionality.Kerri G. LalDohoon KimMargaret C. CostanzoMatthew CreeganEdwin LeeansyahJoana DiasDominic Paquin-ProulxLeigh Anne EllerAlexandra SchuetzYuwadee Phuang-ngernShelly J. KrebsBonnie M. SlikeHannah KibuukaLucas MagangaSorachai NitayaphanJosphat KosgeiCarlo SacdalanJintanat AnanworanichDiane L. BoltonNelson L. MichaelBarbara L. ShacklettMerlin L. RobbMichael A. EllerJohan K. SandbergNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kerri G. Lal Dohoon Kim Margaret C. Costanzo Matthew Creegan Edwin Leeansyah Joana Dias Dominic Paquin-Proulx Leigh Anne Eller Alexandra Schuetz Yuwadee Phuang-ngern Shelly J. Krebs Bonnie M. Slike Hannah Kibuuka Lucas Maganga Sorachai Nitayaphan Josphat Kosgei Carlo Sacdalan Jintanat Ananworanich Diane L. Bolton Nelson L. Michael Barbara L. Shacklett Merlin L. Robb Michael A. Eller Johan K. Sandberg Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection
description	Here, using longitudinal pre- and post-infection samples from the RV217 Early Capture HIV Cohort Study, the authors show that mucosa-associated invariant T (MAIT) cells become activated and expand during the early acute phase of HIV infection, with subsequent reprogramming towards innate-like functionality.
format	article
author	Kerri G. Lal Dohoon Kim Margaret C. Costanzo Matthew Creegan Edwin Leeansyah Joana Dias Dominic Paquin-Proulx Leigh Anne Eller Alexandra Schuetz Yuwadee Phuang-ngern Shelly J. Krebs Bonnie M. Slike Hannah Kibuuka Lucas Maganga Sorachai Nitayaphan Josphat Kosgei Carlo Sacdalan Jintanat Ananworanich Diane L. Bolton Nelson L. Michael Barbara L. Shacklett Merlin L. Robb Michael A. Eller Johan K. Sandberg
author_facet	Kerri G. Lal Dohoon Kim Margaret C. Costanzo Matthew Creegan Edwin Leeansyah Joana Dias Dominic Paquin-Proulx Leigh Anne Eller Alexandra Schuetz Yuwadee Phuang-ngern Shelly J. Krebs Bonnie M. Slike Hannah Kibuuka Lucas Maganga Sorachai Nitayaphan Josphat Kosgei Carlo Sacdalan Jintanat Ananworanich Diane L. Bolton Nelson L. Michael Barbara L. Shacklett Merlin L. Robb Michael A. Eller Johan K. Sandberg
author_sort	Kerri G. Lal
title	Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection
title_short	Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection
title_full	Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection
title_fullStr	Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection
title_full_unstemmed	Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection
title_sort	dynamic mait cell response with progressively enhanced innateness during acute hiv-1 infection
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/bd358f6fc61c41148394e312726032c9
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Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection

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