Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection

Dynamic MAIT cell response with progressively enhanced innateness during acute HIV-1 infection

Here, using longitudinal pre- and post-infection samples from the RV217 Early Capture HIV Cohort Study, the authors show that mucosa-associated invariant T (MAIT) cells become activated and expand during the early acute phase of HIV infection, with subsequent reprogramming towards innate-like functi...

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Autores principales: Kerri G. Lal, Dohoon Kim, Margaret C. Costanzo, Matthew Creegan, Edwin Leeansyah, Joana Dias, Dominic Paquin-Proulx, Leigh Anne Eller, Alexandra Schuetz, Yuwadee Phuang-ngern, Shelly J. Krebs, Bonnie M. Slike, Hannah Kibuuka, Lucas Maganga, Sorachai Nitayaphan, Josphat Kosgei, Carlo Sacdalan, Jintanat Ananworanich, Diane L. Bolton, Nelson L. Michael, Barbara L. Shacklett, Merlin L. Robb, Michael A. Eller, Johan K. Sandberg
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/bd358f6fc61c41148394e312726032c9
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