Infective endocarditis: Role of molecular techniques in early diagnosis

Infective endocarditis (IE), a heart valve infection primarily caused by bacteria such as streptococci or staphylococci, causes significant morbidity and mortality. Despite the long-term use of broad-spectrum antimicrobials, the infection is often difficult to manage. The latest diagnostic modalitie...

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Autores principales:	Abdullah M.K. Albloshi, Mohammed A.A. Alqumber
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2021
Materias:	Infective endocarditis Pathogens Diagnosis Molecular techniques Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/bd3ff078805446d9b075c3fd6a28c51b
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spelling	oai:doaj.org-article:bd3ff078805446d9b075c3fd6a28c51b2021-11-20T04:56:29ZInfective endocarditis: Role of molecular techniques in early diagnosis1319-562X10.1016/j.sjbs.2021.07.060https://doaj.org/article/bd3ff078805446d9b075c3fd6a28c51b2021-12-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1319562X21006446https://doaj.org/toc/1319-562XInfective endocarditis (IE), a heart valve infection primarily caused by bacteria such as streptococci or staphylococci, causes significant morbidity and mortality. Despite the long-term use of broad-spectrum antimicrobials, the infection is often difficult to manage. The latest diagnostic modalities for IE are discussed in this study. Blood culture use in pathogen identification can lead to loss of precious time as well as generation of false negative reports. The first steps in diagnosis are blood cultures and echocardiography, but molecular techniques can be extremely useful and may be used for an accurate and early diagnosis.Abdullah M.K. AlbloshiMohammed A.A. AlqumberElsevierarticleInfective endocarditisPathogensDiagnosisMolecular techniquesBiology (General)QH301-705.5ENSaudi Journal of Biological Sciences, Vol 28, Iss 12, Pp 6844-6852 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Infective endocarditis Pathogens Diagnosis Molecular techniques Biology (General) QH301-705.5
spellingShingle	Infective endocarditis Pathogens Diagnosis Molecular techniques Biology (General) QH301-705.5 Abdullah M.K. Albloshi Mohammed A.A. Alqumber Infective endocarditis: Role of molecular techniques in early diagnosis
description	Infective endocarditis (IE), a heart valve infection primarily caused by bacteria such as streptococci or staphylococci, causes significant morbidity and mortality. Despite the long-term use of broad-spectrum antimicrobials, the infection is often difficult to manage. The latest diagnostic modalities for IE are discussed in this study. Blood culture use in pathogen identification can lead to loss of precious time as well as generation of false negative reports. The first steps in diagnosis are blood cultures and echocardiography, but molecular techniques can be extremely useful and may be used for an accurate and early diagnosis.
format	article
author	Abdullah M.K. Albloshi Mohammed A.A. Alqumber
author_facet	Abdullah M.K. Albloshi Mohammed A.A. Alqumber
author_sort	Abdullah M.K. Albloshi
title	Infective endocarditis: Role of molecular techniques in early diagnosis
title_short	Infective endocarditis: Role of molecular techniques in early diagnosis
title_full	Infective endocarditis: Role of molecular techniques in early diagnosis
title_fullStr	Infective endocarditis: Role of molecular techniques in early diagnosis
title_full_unstemmed	Infective endocarditis: Role of molecular techniques in early diagnosis
title_sort	infective endocarditis: role of molecular techniques in early diagnosis
publisher	Elsevier
publishDate	2021
url	https://doaj.org/article/bd3ff078805446d9b075c3fd6a28c51b
work_keys_str_mv	AT abdullahmkalbloshi infectiveendocarditisroleofmoleculartechniquesinearlydiagnosis AT mohammedaaalqumber infectiveendocarditisroleofmoleculartechniquesinearlydiagnosis
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Infective endocarditis: Role of molecular techniques in early diagnosis

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