Superiority of lymphocyte ratio over total leukocyte count in detecting the severity of COVID- 19 pneumonia

Background: Coronavirus disease (COVID-19) is an infectious disease caused by a recently discovered coronavirus. Blood test including complete blood count is crucial in diagnosing of several viral and bacterial infection. Aims: This study aimed to assess the association between lymphocyte ratio and...

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Autores principales: Rawaa Hadi Shareef, Zinah Dhiaa Zwain, Wadhah Abdulhussian Mahbuba
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/bd60650d953f487384f7b08ca747009b
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Sumario:Background: Coronavirus disease (COVID-19) is an infectious disease caused by a recently discovered coronavirus. Blood test including complete blood count is crucial in diagnosing of several viral and bacterial infection. Aims: This study aimed to assess the association between lymphocyte ratio and other WBC types and severity of COVID-19 pneumonia. Methods: The design of this study was a cross-sectional study. A complete blood count and erythrocyte sedimentation rate (ESR) was done for one hundred twenty-six COVID-19 patients (76 males and 50 females; aged 20–70 years). Patients were randomly recruited from multicenter in Al-Najaf Governorate, Iraq. Results: The study had revealed an inverse correlation between severity of COVID-19 infection and both lymphocytes and monocytes ratio even in patients with normal WBC count. Additionally, there was a direct correlation between platelets and leukocyte count. The relation between leukocyte count and ESR level was significant in a patient with elevated WBC only. Conclusion: Lymphocytes and monocyte ratios inpatient with COVID-19 infection can be used as predictors for the severity of infection. Increased leukocyte count resulted in increases in platelets inpatient with COVID-19.