Multivalent cross-linking of actin filaments and microtubules through the microtubule-associated protein Tau
The microtubule associated protein Tau also interacts with filamentous actin. Here the authors combine biophysical experiments and NMR studies to characterize the structural changes that occur in Tau upon binding to filamentous actin and show that phosphorylation of serine 262 attenuates actin bindi...
Guardado en:
Autores principales: | Yunior Cabrales Fontela, Harindranath Kadavath, Jacek Biernat, Dietmar Riedel, Eckhard Mandelkow, Markus Zweckstetter |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/bd6319513d5748d69c7d46171a874231 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Liquid–liquid phase separation of the microtubule-binding repeats of the Alzheimer-related protein Tau
por: Susmitha Ambadipudi, et al.
Publicado: (2017) -
Tau mediates microtubule bundle architectures mimicking fascicles of microtubules found in the axon initial segment
por: Peter J. Chung, et al.
Publicado: (2016) -
Microtubules as platforms for assaying actin polymerization in vivo.
por: J Margit Oelkers, et al.
Publicado: (2011) -
A key function for microtubule-associated-protein 6 in activity-dependent stabilisation of actin filaments in dendritic spines
por: Leticia Peris, et al.
Publicado: (2018) -
Vimentin intermediate filaments stabilize dynamic microtubules by direct interactions
por: Laura Schaedel, et al.
Publicado: (2021)