T follicular helper and T follicular regulatory cells have different TCR specificity

T follicular helper and regulatory cells are generated in the germinal centre; however, whether antigen specificity defines their differential functions is unclear. Here the authors show that T cells with distinct antigen specificity spectra are recruited to the germinal centre to establish these tw...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ana Raquel Maceiras, Silvia Cristina Paiva Almeida, Encarnita Mariotti-Ferrandiz, Wahiba Chaara, Fadi Jebbawi, Adrien Six, Shohei Hori, David Klatzmann, Jose Faro, Luis Graca
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bd75e21eb1a744808ab34dda848ec107
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:bd75e21eb1a744808ab34dda848ec107
record_format	dspace
spelling	oai:doaj.org-article:bd75e21eb1a744808ab34dda848ec1072021-12-02T14:41:09ZT follicular helper and T follicular regulatory cells have different TCR specificity10.1038/ncomms150672041-1723https://doaj.org/article/bd75e21eb1a744808ab34dda848ec1072017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms15067https://doaj.org/toc/2041-1723T follicular helper and regulatory cells are generated in the germinal centre; however, whether antigen specificity defines their differential functions is unclear. Here the authors show that T cells with distinct antigen specificity spectra are recruited to the germinal centre to establish these two populations.Ana Raquel MaceirasSilvia Cristina Paiva AlmeidaEncarnita Mariotti-FerrandizWahiba ChaaraFadi JebbawiAdrien SixShohei HoriDavid KlatzmannJose FaroLuis GracaNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ana Raquel Maceiras Silvia Cristina Paiva Almeida Encarnita Mariotti-Ferrandiz Wahiba Chaara Fadi Jebbawi Adrien Six Shohei Hori David Klatzmann Jose Faro Luis Graca T follicular helper and T follicular regulatory cells have different TCR specificity
description	T follicular helper and regulatory cells are generated in the germinal centre; however, whether antigen specificity defines their differential functions is unclear. Here the authors show that T cells with distinct antigen specificity spectra are recruited to the germinal centre to establish these two populations.
format	article
author	Ana Raquel Maceiras Silvia Cristina Paiva Almeida Encarnita Mariotti-Ferrandiz Wahiba Chaara Fadi Jebbawi Adrien Six Shohei Hori David Klatzmann Jose Faro Luis Graca
author_facet	Ana Raquel Maceiras Silvia Cristina Paiva Almeida Encarnita Mariotti-Ferrandiz Wahiba Chaara Fadi Jebbawi Adrien Six Shohei Hori David Klatzmann Jose Faro Luis Graca
author_sort	Ana Raquel Maceiras
title	T follicular helper and T follicular regulatory cells have different TCR specificity
title_short	T follicular helper and T follicular regulatory cells have different TCR specificity
title_full	T follicular helper and T follicular regulatory cells have different TCR specificity
title_fullStr	T follicular helper and T follicular regulatory cells have different TCR specificity
title_full_unstemmed	T follicular helper and T follicular regulatory cells have different TCR specificity
title_sort	t follicular helper and t follicular regulatory cells have different tcr specificity
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/bd75e21eb1a744808ab34dda848ec107
work_keys_str_mv	AT anaraquelmaceiras tfollicularhelperandtfollicularregulatorycellshavedifferenttcrspecificity AT silviacristinapaivaalmeida tfollicularhelperandtfollicularregulatorycellshavedifferenttcrspecificity AT encarnitamariottiferrandiz tfollicularhelperandtfollicularregulatorycellshavedifferenttcrspecificity AT wahibachaara tfollicularhelperandtfollicularregulatorycellshavedifferenttcrspecificity AT fadijebbawi tfollicularhelperandtfollicularregulatorycellshavedifferenttcrspecificity AT adriensix tfollicularhelperandtfollicularregulatorycellshavedifferenttcrspecificity AT shoheihori tfollicularhelperandtfollicularregulatorycellshavedifferenttcrspecificity AT davidklatzmann tfollicularhelperandtfollicularregulatorycellshavedifferenttcrspecificity AT josefaro tfollicularhelperandtfollicularregulatorycellshavedifferenttcrspecificity AT luisgraca tfollicularhelperandtfollicularregulatorycellshavedifferenttcrspecificity
_version_	1718390015926468608

T follicular helper and T follicular regulatory cells have different TCR specificity

Ejemplares similares