Photo-induced catalytic halopyridylation of alkenes
The Mizoroki–Heck reaction and its reductive analogue are staples of organic synthesis, but the ensuing products often lack a chemical handle for further transformation. Here the authors present a method to add a heterocycle and transformable halide across a double bond via iridium photocatalysis.
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Nature Portfolio
2021
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oai:doaj.org-article:bd78ed914f094935accf9118a41ebd2d2021-11-14T12:36:25ZPhoto-induced catalytic halopyridylation of alkenes10.1038/s41467-021-26857-w2041-1723https://doaj.org/article/bd78ed914f094935accf9118a41ebd2d2021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26857-whttps://doaj.org/toc/2041-1723The Mizoroki–Heck reaction and its reductive analogue are staples of organic synthesis, but the ensuing products often lack a chemical handle for further transformation. Here the authors present a method to add a heterocycle and transformable halide across a double bond via iridium photocatalysis.Shi-Yu GuoFan YangTing-Ting SongYu-Qing GuanXiang-Ting MinDing-Wei JiYan-Cheng HuQing-An ChenNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-9 (2021) |
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Science Q Shi-Yu Guo Fan Yang Ting-Ting Song Yu-Qing Guan Xiang-Ting Min Ding-Wei Ji Yan-Cheng Hu Qing-An Chen Photo-induced catalytic halopyridylation of alkenes |
description |
The Mizoroki–Heck reaction and its reductive analogue are staples of organic synthesis, but the ensuing products often lack a chemical handle for further transformation. Here the authors present a method to add a heterocycle and transformable halide across a double bond via iridium photocatalysis. |
format |
article |
author |
Shi-Yu Guo Fan Yang Ting-Ting Song Yu-Qing Guan Xiang-Ting Min Ding-Wei Ji Yan-Cheng Hu Qing-An Chen |
author_facet |
Shi-Yu Guo Fan Yang Ting-Ting Song Yu-Qing Guan Xiang-Ting Min Ding-Wei Ji Yan-Cheng Hu Qing-An Chen |
author_sort |
Shi-Yu Guo |
title |
Photo-induced catalytic halopyridylation of alkenes |
title_short |
Photo-induced catalytic halopyridylation of alkenes |
title_full |
Photo-induced catalytic halopyridylation of alkenes |
title_fullStr |
Photo-induced catalytic halopyridylation of alkenes |
title_full_unstemmed |
Photo-induced catalytic halopyridylation of alkenes |
title_sort |
photo-induced catalytic halopyridylation of alkenes |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/bd78ed914f094935accf9118a41ebd2d |
work_keys_str_mv |
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_version_ |
1718429128236990464 |