Investigating sensory response to physical discomfort in children with autism spectrum disorder using near-infrared spectroscopy.

Self-reporting of pain can be difficult in populations with communication challenges or atypical sensory processing, such as children with autism spectrum disorder (ASD). Consequently, pain can go untreated. An objective method to identify discomfort would be valuable to individuals unable to expres...

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Autores principales:	Larissa C Schudlo, Evdokia Anagnostou, Tom Chau, Krissy Doyle-Thomas
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/bd89ea5f232a422da29b15f39740adc0
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spelling	oai:doaj.org-article:bd89ea5f232a422da29b15f39740adc02021-12-02T20:08:31ZInvestigating sensory response to physical discomfort in children with autism spectrum disorder using near-infrared spectroscopy.1932-620310.1371/journal.pone.0257029https://doaj.org/article/bd89ea5f232a422da29b15f39740adc02021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0257029https://doaj.org/toc/1932-6203Self-reporting of pain can be difficult in populations with communication challenges or atypical sensory processing, such as children with autism spectrum disorder (ASD). Consequently, pain can go untreated. An objective method to identify discomfort would be valuable to individuals unable to express or recognize their own bodily distress. Near-infrared spectroscopy (NIRS) is a brain-imaging modality that is suited for this application. We evaluated the potential of detecting a cortical response to discomfort in the ASD population using NIRS. Using a continuous-wave spectrometer, prefrontal and parietal measures were collected from 15 males with ASD and 7 typically developing (TD) males 10-15 years of age. Participants were exposed to a noxious cold stimulus by immersing their hands in cold water and tepid water as a baseline task. Across all participants, the magnitude and timing of the cold and tepid water-induced brain responses were significantly different (p < 0.001). The effect of the task on the brain response depended on the study group (group x task: p < 0.001), with the ASD group exhibiting a blunted response to the cold stimulus. Findings suggest that NIRS may serve as a tool for objective pain assessment and atypical sensory processing.Larissa C SchudloEvdokia AnagnostouTom ChauKrissy Doyle-ThomasPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 9, p e0257029 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Larissa C Schudlo Evdokia Anagnostou Tom Chau Krissy Doyle-Thomas Investigating sensory response to physical discomfort in children with autism spectrum disorder using near-infrared spectroscopy.
description	Self-reporting of pain can be difficult in populations with communication challenges or atypical sensory processing, such as children with autism spectrum disorder (ASD). Consequently, pain can go untreated. An objective method to identify discomfort would be valuable to individuals unable to express or recognize their own bodily distress. Near-infrared spectroscopy (NIRS) is a brain-imaging modality that is suited for this application. We evaluated the potential of detecting a cortical response to discomfort in the ASD population using NIRS. Using a continuous-wave spectrometer, prefrontal and parietal measures were collected from 15 males with ASD and 7 typically developing (TD) males 10-15 years of age. Participants were exposed to a noxious cold stimulus by immersing their hands in cold water and tepid water as a baseline task. Across all participants, the magnitude and timing of the cold and tepid water-induced brain responses were significantly different (p < 0.001). The effect of the task on the brain response depended on the study group (group x task: p < 0.001), with the ASD group exhibiting a blunted response to the cold stimulus. Findings suggest that NIRS may serve as a tool for objective pain assessment and atypical sensory processing.
format	article
author	Larissa C Schudlo Evdokia Anagnostou Tom Chau Krissy Doyle-Thomas
author_facet	Larissa C Schudlo Evdokia Anagnostou Tom Chau Krissy Doyle-Thomas
author_sort	Larissa C Schudlo
title	Investigating sensory response to physical discomfort in children with autism spectrum disorder using near-infrared spectroscopy.
title_short	Investigating sensory response to physical discomfort in children with autism spectrum disorder using near-infrared spectroscopy.
title_full	Investigating sensory response to physical discomfort in children with autism spectrum disorder using near-infrared spectroscopy.
title_fullStr	Investigating sensory response to physical discomfort in children with autism spectrum disorder using near-infrared spectroscopy.
title_full_unstemmed	Investigating sensory response to physical discomfort in children with autism spectrum disorder using near-infrared spectroscopy.
title_sort	investigating sensory response to physical discomfort in children with autism spectrum disorder using near-infrared spectroscopy.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/bd89ea5f232a422da29b15f39740adc0
work_keys_str_mv	AT larissacschudlo investigatingsensoryresponsetophysicaldiscomfortinchildrenwithautismspectrumdisorderusingnearinfraredspectroscopy AT evdokiaanagnostou investigatingsensoryresponsetophysicaldiscomfortinchildrenwithautismspectrumdisorderusingnearinfraredspectroscopy AT tomchau investigatingsensoryresponsetophysicaldiscomfortinchildrenwithautismspectrumdisorderusingnearinfraredspectroscopy AT krissydoylethomas investigatingsensoryresponsetophysicaldiscomfortinchildrenwithautismspectrumdisorderusingnearinfraredspectroscopy
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Investigating sensory response to physical discomfort in children with autism spectrum disorder using near-infrared spectroscopy.

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