Identification of a Zeb1 expressing basal stem cell subpopulation in the prostate

Heterogeneous populations of basal cells in the prostate epithelium contain stem cells. Here the authors show that Zeb1 marks a pool of prostate epithelial stem cells that self-renew, generate prostate glandular structures with all 3 epithelial cell types and are required for prostate basal cell dev...

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Autores principales:	Xue Wang, Haibo Xu, Chaping Cheng, Zhongzhong Ji, Huifang Zhao, Yaru Sheng, Xiaoxia Li, Jinming Wang, Yu Shu, Yuman He, Liancheng Fan, Baijun Dong, Wei Xue, Chee Wai Chua, Dongdong Wu, Wei-Qiang Gao, Helen He Zhu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bd8edfecd5cc4953a997a60f4c5ace58
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spelling	oai:doaj.org-article:bd8edfecd5cc4953a997a60f4c5ace582021-12-02T17:33:14ZIdentification of a Zeb1 expressing basal stem cell subpopulation in the prostate10.1038/s41467-020-14296-y2041-1723https://doaj.org/article/bd8edfecd5cc4953a997a60f4c5ace582020-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14296-yhttps://doaj.org/toc/2041-1723Heterogeneous populations of basal cells in the prostate epithelium contain stem cells. Here the authors show that Zeb1 marks a pool of prostate epithelial stem cells that self-renew, generate prostate glandular structures with all 3 epithelial cell types and are required for prostate basal cell development.Xue WangHaibo XuChaping ChengZhongzhong JiHuifang ZhaoYaru ShengXiaoxia LiJinming WangYu ShuYuman HeLiancheng FanBaijun DongWei XueChee Wai ChuaDongdong WuWei-Qiang GaoHelen He ZhuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xue Wang Haibo Xu Chaping Cheng Zhongzhong Ji Huifang Zhao Yaru Sheng Xiaoxia Li Jinming Wang Yu Shu Yuman He Liancheng Fan Baijun Dong Wei Xue Chee Wai Chua Dongdong Wu Wei-Qiang Gao Helen He Zhu Identification of a Zeb1 expressing basal stem cell subpopulation in the prostate
description	Heterogeneous populations of basal cells in the prostate epithelium contain stem cells. Here the authors show that Zeb1 marks a pool of prostate epithelial stem cells that self-renew, generate prostate glandular structures with all 3 epithelial cell types and are required for prostate basal cell development.
format	article
author	Xue Wang Haibo Xu Chaping Cheng Zhongzhong Ji Huifang Zhao Yaru Sheng Xiaoxia Li Jinming Wang Yu Shu Yuman He Liancheng Fan Baijun Dong Wei Xue Chee Wai Chua Dongdong Wu Wei-Qiang Gao Helen He Zhu
author_facet	Xue Wang Haibo Xu Chaping Cheng Zhongzhong Ji Huifang Zhao Yaru Sheng Xiaoxia Li Jinming Wang Yu Shu Yuman He Liancheng Fan Baijun Dong Wei Xue Chee Wai Chua Dongdong Wu Wei-Qiang Gao Helen He Zhu
author_sort	Xue Wang
title	Identification of a Zeb1 expressing basal stem cell subpopulation in the prostate
title_short	Identification of a Zeb1 expressing basal stem cell subpopulation in the prostate
title_full	Identification of a Zeb1 expressing basal stem cell subpopulation in the prostate
title_fullStr	Identification of a Zeb1 expressing basal stem cell subpopulation in the prostate
title_full_unstemmed	Identification of a Zeb1 expressing basal stem cell subpopulation in the prostate
title_sort	identification of a zeb1 expressing basal stem cell subpopulation in the prostate
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/bd8edfecd5cc4953a997a60f4c5ace58
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Identification of a Zeb1 expressing basal stem cell subpopulation in the prostate

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