Template-directed RNA polymerization and enhanced ribozyme catalysis inside membraneless compartments formed by coacervates

Membraneless compartments have been theorized to be prebiotic micro-compartments as they spontaneously encapsulate RNA and proteins. Here, the authors report membraneless compartments can enhance RNA chemistries, affecting template directed RNA polymerization and stimulating nucleic acid enzymes.

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Autores principales:	Raghav R. Poudyal, Rebecca M. Guth-Metzler, Andrew J. Veenis, Erica A. Frankel, Christine D. Keating, Philip C. Bevilacqua
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bd95f9acb3e540aebabd151c0ada12ad
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spelling	oai:doaj.org-article:bd95f9acb3e540aebabd151c0ada12ad2021-12-02T14:35:51ZTemplate-directed RNA polymerization and enhanced ribozyme catalysis inside membraneless compartments formed by coacervates10.1038/s41467-019-08353-42041-1723https://doaj.org/article/bd95f9acb3e540aebabd151c0ada12ad2019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08353-4https://doaj.org/toc/2041-1723Membraneless compartments have been theorized to be prebiotic micro-compartments as they spontaneously encapsulate RNA and proteins. Here, the authors report membraneless compartments can enhance RNA chemistries, affecting template directed RNA polymerization and stimulating nucleic acid enzymes.Raghav R. PoudyalRebecca M. Guth-MetzlerAndrew J. VeenisErica A. FrankelChristine D. KeatingPhilip C. BevilacquaNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Raghav R. Poudyal Rebecca M. Guth-Metzler Andrew J. Veenis Erica A. Frankel Christine D. Keating Philip C. Bevilacqua Template-directed RNA polymerization and enhanced ribozyme catalysis inside membraneless compartments formed by coacervates
description	Membraneless compartments have been theorized to be prebiotic micro-compartments as they spontaneously encapsulate RNA and proteins. Here, the authors report membraneless compartments can enhance RNA chemistries, affecting template directed RNA polymerization and stimulating nucleic acid enzymes.
format	article
author	Raghav R. Poudyal Rebecca M. Guth-Metzler Andrew J. Veenis Erica A. Frankel Christine D. Keating Philip C. Bevilacqua
author_facet	Raghav R. Poudyal Rebecca M. Guth-Metzler Andrew J. Veenis Erica A. Frankel Christine D. Keating Philip C. Bevilacqua
author_sort	Raghav R. Poudyal
title	Template-directed RNA polymerization and enhanced ribozyme catalysis inside membraneless compartments formed by coacervates
title_short	Template-directed RNA polymerization and enhanced ribozyme catalysis inside membraneless compartments formed by coacervates
title_full	Template-directed RNA polymerization and enhanced ribozyme catalysis inside membraneless compartments formed by coacervates
title_fullStr	Template-directed RNA polymerization and enhanced ribozyme catalysis inside membraneless compartments formed by coacervates
title_full_unstemmed	Template-directed RNA polymerization and enhanced ribozyme catalysis inside membraneless compartments formed by coacervates
title_sort	template-directed rna polymerization and enhanced ribozyme catalysis inside membraneless compartments formed by coacervates
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/bd95f9acb3e540aebabd151c0ada12ad
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Template-directed RNA polymerization and enhanced ribozyme catalysis inside membraneless compartments formed by coacervates

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