Site-specific incorporation of citrulline into proteins in mammalian cells

Site-specific incorporation of citrulline into proteins in mammalian cells

Citrullination of arginine is crucial for several physiological processes. Here the authors report the site-specific incorporation of citrulline into proteins in mammalian cells using an engineered tRNA synthetase/tRNA pair and a photocaged-citrulline.

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Autores principales: Santanu Mondal, Shu Wang, Yunan Zheng, Sudeshna Sen, Abhishek Chatterjee, Paul R. Thompson
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
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Acceso en línea:https://doaj.org/article/bd9c1f5a80e24b4ca721bf1b4716c16e
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