Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes

Histone H2A monoubiquitination on lysine 119 in vertebrate and lysine 118 in Drosophila (H2Aub) is an epigenomic mark usually associated with gene repression by Polycomb group factors. Here the authors review the current knowledge on the deposition and removal of H2Aub, its function in transcription...

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Autores principales:	Haithem Barbour, Salima Daou, Michael Hendzel, El Bachir Affar
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bd9ef5e9d7494f88a04d126380621916
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spelling	oai:doaj.org-article:bd9ef5e9d7494f88a04d1263806219162021-12-02T10:48:29ZPolycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes10.1038/s41467-020-19722-92041-1723https://doaj.org/article/bd9ef5e9d7494f88a04d1263806219162020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19722-9https://doaj.org/toc/2041-1723Histone H2A monoubiquitination on lysine 119 in vertebrate and lysine 118 in Drosophila (H2Aub) is an epigenomic mark usually associated with gene repression by Polycomb group factors. Here the authors review the current knowledge on the deposition and removal of H2Aub, its function in transcription and other DNA-associated processes as well as its relevance to human disease.Haithem BarbourSalima DaouMichael HendzelEl Bachir AffarNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Haithem Barbour Salima Daou Michael Hendzel El Bachir Affar Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes
description	Histone H2A monoubiquitination on lysine 119 in vertebrate and lysine 118 in Drosophila (H2Aub) is an epigenomic mark usually associated with gene repression by Polycomb group factors. Here the authors review the current knowledge on the deposition and removal of H2Aub, its function in transcription and other DNA-associated processes as well as its relevance to human disease.
format	article
author	Haithem Barbour Salima Daou Michael Hendzel El Bachir Affar
author_facet	Haithem Barbour Salima Daou Michael Hendzel El Bachir Affar
author_sort	Haithem Barbour
title	Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes
title_short	Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes
title_full	Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes
title_fullStr	Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes
title_full_unstemmed	Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes
title_sort	polycomb group-mediated histone h2a monoubiquitination in epigenome regulation and nuclear processes
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/bd9ef5e9d7494f88a04d126380621916
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Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes

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