Polycomb group-mediated histone H2A monoubiquitination in epigenome regulation and nuclear processes

Histone H2A monoubiquitination on lysine 119 in vertebrate and lysine 118 in Drosophila (H2Aub) is an epigenomic mark usually associated with gene repression by Polycomb group factors. Here the authors review the current knowledge on the deposition and removal of H2Aub, its function in transcription...

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Autores principales: Haithem Barbour, Salima Daou, Michael Hendzel, El Bachir Affar
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/bd9ef5e9d7494f88a04d126380621916
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