Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation
Multivariate analysis methods can uncover the relationship between phenotypic measures characterised by modern omic techniques. Here the authors conduct a multivariate GWAS on IgG N-glycosylation phenotypes and identify 5 novel loci enriched in immune system genes.
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Nature Portfolio
2017
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oai:doaj.org-article:bdb377dc33c14ec3bcd9b3939264bdb92021-12-02T17:06:24ZMultivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation10.1038/s41467-017-00453-32041-1723https://doaj.org/article/bdb377dc33c14ec3bcd9b3939264bdb92017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00453-3https://doaj.org/toc/2041-1723Multivariate analysis methods can uncover the relationship between phenotypic measures characterised by modern omic techniques. Here the authors conduct a multivariate GWAS on IgG N-glycosylation phenotypes and identify 5 novel loci enriched in immune system genes.Xia ShenLucija KlarićSodbo SharapovMassimo ManginoZheng NingDi WuIrena Trbojević-AkmačićMaja Pučić-BakovićIgor RudanOzren PolašekCaroline HaywardTimothy D. SpectorJames F. WilsonGordan LaucYurii S. AulchenkoNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Xia Shen Lucija Klarić Sodbo Sharapov Massimo Mangino Zheng Ning Di Wu Irena Trbojević-Akmačić Maja Pučić-Baković Igor Rudan Ozren Polašek Caroline Hayward Timothy D. Spector James F. Wilson Gordan Lauc Yurii S. Aulchenko Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation |
| description |
Multivariate analysis methods can uncover the relationship between phenotypic measures characterised by modern omic techniques. Here the authors conduct a multivariate GWAS on IgG N-glycosylation phenotypes and identify 5 novel loci enriched in immune system genes. |
| format |
article |
| author |
Xia Shen Lucija Klarić Sodbo Sharapov Massimo Mangino Zheng Ning Di Wu Irena Trbojević-Akmačić Maja Pučić-Baković Igor Rudan Ozren Polašek Caroline Hayward Timothy D. Spector James F. Wilson Gordan Lauc Yurii S. Aulchenko |
| author_facet |
Xia Shen Lucija Klarić Sodbo Sharapov Massimo Mangino Zheng Ning Di Wu Irena Trbojević-Akmačić Maja Pučić-Baković Igor Rudan Ozren Polašek Caroline Hayward Timothy D. Spector James F. Wilson Gordan Lauc Yurii S. Aulchenko |
| author_sort |
Xia Shen |
| title |
Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation |
| title_short |
Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation |
| title_full |
Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation |
| title_fullStr |
Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation |
| title_full_unstemmed |
Multivariate discovery and replication of five novel loci associated with Immunoglobulin G N-glycosylation |
| title_sort |
multivariate discovery and replication of five novel loci associated with immunoglobulin g n-glycosylation |
| publisher |
Nature Portfolio |
| publishDate |
2017 |
| url |
https://doaj.org/article/bdb377dc33c14ec3bcd9b3939264bdb9 |
| work_keys_str_mv |
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