STING-Dependent Recognition of Cyclic di-AMP Mediates Type I Interferon Responses during <named-content content-type="genus-species">Chlamydia trachomatis</named-content> Infection

STING-Dependent Recognition of Cyclic di-AMP Mediates Type I Interferon Responses during <named-content content-type="genus-species">Chlamydia trachomatis</named-content> Infection

ABSTRACT STING (stimulator of interferon [IFN] genes) initiates type I IFN responses in mammalian cells through the detection of microbial nucleic acids. The membrane-bound obligate intracellular bacterium Chlamydia trachomatis induces a STING-dependent type I IFN response in infected cells, yet the...

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Autores principales: Jeffrey R. Barker, Benjamin J. Koestler, Victoria K. Carpenter, Dara L. Burdette, Christopher M. Waters, Russell E. Vance, Raphael H. Valdivia
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2013
Materias:
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/bdb5532bc2164aa296238bf6a6386812
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