Intermittent Use of a Short-Course Glucagon-like Peptide-1 Receptor Agonist Therapy Limits Adverse Cardiac Remodeling via Parkin-dependent Mitochondrial Turnover

Intermittent Use of a Short-Course Glucagon-like Peptide-1 Receptor Agonist Therapy Limits Adverse Cardiac Remodeling via Parkin-dependent Mitochondrial Turnover

Abstract Given that adverse remodeling is the leading cause of heart failure and death in the USA, there is an urgent unmet need to develop new methods in dealing with this devastating disease. Here we evaluated the efficacy of a short-course glucagon-like peptide-1 receptor agonist therapy—specific...

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Autores principales: Juliana de F. Germano, Chengqun Huang, Jon Sin, Yang Song, Kyle C. Tucker, David J. R. Taylor, Hannaneh Saadaeijahromi, Aleksandr Stotland, Honit Piplani, Roberta A. Gottlieb, Robert M. Mentzer, Allen M. Andres
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/bdb64149fffc46618c22d0b61e814c7a
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