Epidemiology and mortality of liver abscess in end-stage renal disease dialysis patients: Taiwan national cohort study.

<h4>Background and objectives</h4>To determine the incidence rates and mortality of liver abscess in ESRD patients on dialysis.<h4>Design setting participants & measurements</h4>Using Taiwan's National Health Insurance Research Database, we collected data from all ES...

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Autores principales: Chon-Seng Hong, Kun-Ming Chung, Po-Chang Huang, Jhi-Joung Wang, Chun-Ming Yang, Chin-Chen Chu, Chung-Ching Chio, Fu-Lin Chang, Chih-Chiang Chien
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Publicado: Public Library of Science (PLoS) 2014
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spelling oai:doaj.org-article:bdd1428f8317493fa0b6d4a074eb77d62021-11-18T08:32:30ZEpidemiology and mortality of liver abscess in end-stage renal disease dialysis patients: Taiwan national cohort study.1932-620310.1371/journal.pone.0088078https://doaj.org/article/bdd1428f8317493fa0b6d4a074eb77d62014-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24551077/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background and objectives</h4>To determine the incidence rates and mortality of liver abscess in ESRD patients on dialysis.<h4>Design setting participants & measurements</h4>Using Taiwan's National Health Insurance Research Database, we collected data from all ESRD patients who initiated dialysis between 2000 and 2006. Patients were followed until death, end of dialysis, or December 31, 2008. Predictors of liver abscess and mortality were identified using Cox models.<h4>Results</h4>Of the 53,249 incident dialysis patients identified, 447 were diagnosed as having liver abscesses during the follow-up period (224/100,000 person-years). The cumulative incidence rate of liver abscess was 0.3%, 1.1%, and 1.5% at 1 year, 5 years, and 7 years, respectively. Elderly patients and patients on peritoneal dialysis had higher incidence rates. The baseline comorbidities of diabetes mellitus, polycystic kidney disease, malignancy, chronic liver disease, biliary tract disease, or alcoholism predicted development of liver abscess. Overall in-hospital mortality was 10.1%.<h4>Conclusions</h4>The incidence of liver abscess is high among ESRD dialysis patients. In addition to the well known risk factors of liver abscess, two other important risk factors, peritoneal dialysis and polycystic kidney disease, were found to predict liver abscess in ESRD dialysis patients.Chon-Seng HongKun-Ming ChungPo-Chang HuangJhi-Joung WangChun-Ming YangChin-Chen ChuChung-Ching ChioFu-Lin ChangChih-Chiang ChienPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 9, Iss 2, p e88078 (2014)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
Science
Q
spellingShingle Medicine
R
Science
Q
Chon-Seng Hong
Kun-Ming Chung
Po-Chang Huang
Jhi-Joung Wang
Chun-Ming Yang
Chin-Chen Chu
Chung-Ching Chio
Fu-Lin Chang
Chih-Chiang Chien
Epidemiology and mortality of liver abscess in end-stage renal disease dialysis patients: Taiwan national cohort study.
description <h4>Background and objectives</h4>To determine the incidence rates and mortality of liver abscess in ESRD patients on dialysis.<h4>Design setting participants & measurements</h4>Using Taiwan's National Health Insurance Research Database, we collected data from all ESRD patients who initiated dialysis between 2000 and 2006. Patients were followed until death, end of dialysis, or December 31, 2008. Predictors of liver abscess and mortality were identified using Cox models.<h4>Results</h4>Of the 53,249 incident dialysis patients identified, 447 were diagnosed as having liver abscesses during the follow-up period (224/100,000 person-years). The cumulative incidence rate of liver abscess was 0.3%, 1.1%, and 1.5% at 1 year, 5 years, and 7 years, respectively. Elderly patients and patients on peritoneal dialysis had higher incidence rates. The baseline comorbidities of diabetes mellitus, polycystic kidney disease, malignancy, chronic liver disease, biliary tract disease, or alcoholism predicted development of liver abscess. Overall in-hospital mortality was 10.1%.<h4>Conclusions</h4>The incidence of liver abscess is high among ESRD dialysis patients. In addition to the well known risk factors of liver abscess, two other important risk factors, peritoneal dialysis and polycystic kidney disease, were found to predict liver abscess in ESRD dialysis patients.
format article
author Chon-Seng Hong
Kun-Ming Chung
Po-Chang Huang
Jhi-Joung Wang
Chun-Ming Yang
Chin-Chen Chu
Chung-Ching Chio
Fu-Lin Chang
Chih-Chiang Chien
author_facet Chon-Seng Hong
Kun-Ming Chung
Po-Chang Huang
Jhi-Joung Wang
Chun-Ming Yang
Chin-Chen Chu
Chung-Ching Chio
Fu-Lin Chang
Chih-Chiang Chien
author_sort Chon-Seng Hong
title Epidemiology and mortality of liver abscess in end-stage renal disease dialysis patients: Taiwan national cohort study.
title_short Epidemiology and mortality of liver abscess in end-stage renal disease dialysis patients: Taiwan national cohort study.
title_full Epidemiology and mortality of liver abscess in end-stage renal disease dialysis patients: Taiwan national cohort study.
title_fullStr Epidemiology and mortality of liver abscess in end-stage renal disease dialysis patients: Taiwan national cohort study.
title_full_unstemmed Epidemiology and mortality of liver abscess in end-stage renal disease dialysis patients: Taiwan national cohort study.
title_sort epidemiology and mortality of liver abscess in end-stage renal disease dialysis patients: taiwan national cohort study.
publisher Public Library of Science (PLoS)
publishDate 2014
url https://doaj.org/article/bdd1428f8317493fa0b6d4a074eb77d6
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