The genetic architecture of sporadic and multiple consecutive miscarriage

Miscarriage affects around 15% of clinically confirmed pregnancies. Here the authors carry out a large genome-wide association study for sporadic and multiple consecutive miscarriage and suggest links with placental biology.

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Autores principales: Triin Laisk, Ana Luiza G. Soares, Teresa Ferreira, Jodie N. Painter, Jenny C. Censin, Samantha Laber, Jonas Bacelis, Chia-Yen Chen, Maarja Lepamets, Kuang Lin, Siyang Liu, Iona Y. Millwood, Avinash Ramu, Jennifer Southcombe, Marianne S. Andersen, Ling Yang, Christian M. Becker, Anders D. Børglum, Scott D. Gordon, Jonas Bybjerg-Grauholm, Øyvind Helgeland, David M. Hougaard, Xin Jin, Stefan Johansson, Julius Juodakis, Christiana Kartsonaki, Viktorija Kukushkina, Penelope A. Lind, Andres Metspalu, Grant W. Montgomery, Andrew P. Morris, Ole Mors, Preben B. Mortensen, Pål R. Njølstad, Merete Nordentoft, Dale R. Nyholt, Margaret Lippincott, Stephanie Seminara, Andres Salumets, Harold Snieder, Krina Zondervan, Thomas Werge, Zhengming Chen, Donald F. Conrad, Bo Jacobsson, Liming Li, Nicholas G. Martin, Benjamin M. Neale, Rasmus Nielsen, Robin G. Walters, Ingrid Granne, Sarah E. Medland, Reedik Mägi, Deborah A. Lawlor, Cecilia M. Lindgren
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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spelling oai:doaj.org-article:bdd3d54f8cfb46f29d8530d41ddbc34a2021-12-02T13:57:33ZThe genetic architecture of sporadic and multiple consecutive miscarriage10.1038/s41467-020-19742-52041-1723https://doaj.org/article/bdd3d54f8cfb46f29d8530d41ddbc34a2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19742-5https://doaj.org/toc/2041-1723Miscarriage affects around 15% of clinically confirmed pregnancies. Here the authors carry out a large genome-wide association study for sporadic and multiple consecutive miscarriage and suggest links with placental biology.Triin LaiskAna Luiza G. SoaresTeresa FerreiraJodie N. PainterJenny C. CensinSamantha LaberJonas BacelisChia-Yen ChenMaarja LepametsKuang LinSiyang LiuIona Y. MillwoodAvinash RamuJennifer SouthcombeMarianne S. AndersenLing YangChristian M. BeckerAnders D. BørglumScott D. GordonJonas Bybjerg-GrauholmØyvind HelgelandDavid M. HougaardXin JinStefan JohanssonJulius JuodakisChristiana KartsonakiViktorija KukushkinaPenelope A. LindAndres MetspaluGrant W. MontgomeryAndrew P. MorrisOle MorsPreben B. MortensenPål R. NjølstadMerete NordentoftDale R. NyholtMargaret LippincottStephanie SeminaraAndres SalumetsHarold SniederKrina ZondervanThomas WergeZhengming ChenDonald F. ConradBo JacobssonLiming LiNicholas G. MartinBenjamin M. NealeRasmus NielsenRobin G. WaltersIngrid GranneSarah E. MedlandReedik MägiDeborah A. LawlorCecilia M. LindgrenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Triin Laisk
Ana Luiza G. Soares
Teresa Ferreira
Jodie N. Painter
Jenny C. Censin
Samantha Laber
Jonas Bacelis
Chia-Yen Chen
Maarja Lepamets
Kuang Lin
Siyang Liu
Iona Y. Millwood
Avinash Ramu
Jennifer Southcombe
Marianne S. Andersen
Ling Yang
Christian M. Becker
Anders D. Børglum
Scott D. Gordon
Jonas Bybjerg-Grauholm
Øyvind Helgeland
David M. Hougaard
Xin Jin
Stefan Johansson
Julius Juodakis
Christiana Kartsonaki
Viktorija Kukushkina
Penelope A. Lind
Andres Metspalu
Grant W. Montgomery
Andrew P. Morris
Ole Mors
Preben B. Mortensen
Pål R. Njølstad
Merete Nordentoft
Dale R. Nyholt
Margaret Lippincott
Stephanie Seminara
Andres Salumets
Harold Snieder
Krina Zondervan
Thomas Werge
Zhengming Chen
Donald F. Conrad
Bo Jacobsson
Liming Li
Nicholas G. Martin
Benjamin M. Neale
Rasmus Nielsen
Robin G. Walters
Ingrid Granne
Sarah E. Medland
Reedik Mägi
Deborah A. Lawlor
Cecilia M. Lindgren
The genetic architecture of sporadic and multiple consecutive miscarriage
description Miscarriage affects around 15% of clinically confirmed pregnancies. Here the authors carry out a large genome-wide association study for sporadic and multiple consecutive miscarriage and suggest links with placental biology.
format article
author Triin Laisk
Ana Luiza G. Soares
Teresa Ferreira
Jodie N. Painter
Jenny C. Censin
Samantha Laber
Jonas Bacelis
Chia-Yen Chen
Maarja Lepamets
Kuang Lin
Siyang Liu
Iona Y. Millwood
Avinash Ramu
Jennifer Southcombe
Marianne S. Andersen
Ling Yang
Christian M. Becker
Anders D. Børglum
Scott D. Gordon
Jonas Bybjerg-Grauholm
Øyvind Helgeland
David M. Hougaard
Xin Jin
Stefan Johansson
Julius Juodakis
Christiana Kartsonaki
Viktorija Kukushkina
Penelope A. Lind
Andres Metspalu
Grant W. Montgomery
Andrew P. Morris
Ole Mors
Preben B. Mortensen
Pål R. Njølstad
Merete Nordentoft
Dale R. Nyholt
Margaret Lippincott
Stephanie Seminara
Andres Salumets
Harold Snieder
Krina Zondervan
Thomas Werge
Zhengming Chen
Donald F. Conrad
Bo Jacobsson
Liming Li
Nicholas G. Martin
Benjamin M. Neale
Rasmus Nielsen
Robin G. Walters
Ingrid Granne
Sarah E. Medland
Reedik Mägi
Deborah A. Lawlor
Cecilia M. Lindgren
author_facet Triin Laisk
Ana Luiza G. Soares
Teresa Ferreira
Jodie N. Painter
Jenny C. Censin
Samantha Laber
Jonas Bacelis
Chia-Yen Chen
Maarja Lepamets
Kuang Lin
Siyang Liu
Iona Y. Millwood
Avinash Ramu
Jennifer Southcombe
Marianne S. Andersen
Ling Yang
Christian M. Becker
Anders D. Børglum
Scott D. Gordon
Jonas Bybjerg-Grauholm
Øyvind Helgeland
David M. Hougaard
Xin Jin
Stefan Johansson
Julius Juodakis
Christiana Kartsonaki
Viktorija Kukushkina
Penelope A. Lind
Andres Metspalu
Grant W. Montgomery
Andrew P. Morris
Ole Mors
Preben B. Mortensen
Pål R. Njølstad
Merete Nordentoft
Dale R. Nyholt
Margaret Lippincott
Stephanie Seminara
Andres Salumets
Harold Snieder
Krina Zondervan
Thomas Werge
Zhengming Chen
Donald F. Conrad
Bo Jacobsson
Liming Li
Nicholas G. Martin
Benjamin M. Neale
Rasmus Nielsen
Robin G. Walters
Ingrid Granne
Sarah E. Medland
Reedik Mägi
Deborah A. Lawlor
Cecilia M. Lindgren
author_sort Triin Laisk
title The genetic architecture of sporadic and multiple consecutive miscarriage
title_short The genetic architecture of sporadic and multiple consecutive miscarriage
title_full The genetic architecture of sporadic and multiple consecutive miscarriage
title_fullStr The genetic architecture of sporadic and multiple consecutive miscarriage
title_full_unstemmed The genetic architecture of sporadic and multiple consecutive miscarriage
title_sort genetic architecture of sporadic and multiple consecutive miscarriage
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/bdd3d54f8cfb46f29d8530d41ddbc34a
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