Bronchial smooth muscle cells of asthmatics promote angiogenesis through elevated secretion of CXC-chemokines (ENA-78, GRO-α, and IL-8).

Bronchial smooth muscle cells of asthmatics promote angiogenesis through elevated secretion of CXC-chemokines (ENA-78, GRO-α, and IL-8).

<h4>Background</h4>Airway wall remodelling is a key pathology of asthma. It includes thickening of the airway wall, hypertrophy and hyperplasia of bronchial smooth muscle cells (BSMC), as well as an increased vascularity of the sub-epithelial cell layer. BSMC are known to be the effector...

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Autores principales: Laura Keglowich, Michael Roth, Maria Philippova, Thérèse Resink, Gavin Tjin, Brian Oliver, Didier Lardinois, Sophie Dessus-Babus, Reinoud Gosens, Katrin Hostettler Haack, Michael Tamm, Peter Borger
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
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Science
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Acceso en línea:https://doaj.org/article/bdd7199be21c434f8aa214c3432b9e59
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