Dynamic Model Visualizing the Process of Viral Plaque Formation

In Microbiology and Virology courses, viral plaques are often presented to students as the way one can visualize viruses/bacteriophages. While students generally grasp the idea that counting plaques is essentially the same as counting viruses in their sample (assuming that one virus entering the cel...

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Autor principal: Boriana Marintcheva
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Lenguaje:EN
Publicado: American Society for Microbiology 2012
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spelling oai:doaj.org-article:bdd8c6bb94744cf786118210f57306402021-11-15T15:03:40ZDynamic Model Visualizing the Process of Viral Plaque Formation10.1128/jmbe.v13i2.4321935-78851935-7877https://doaj.org/article/bdd8c6bb94744cf786118210f57306402012-01-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/jmbe.v13i2.432https://doaj.org/toc/1935-7877https://doaj.org/toc/1935-7885In Microbiology and Virology courses, viral plaques are often presented to students as the way one can visualize viruses/bacteriophages. While students generally grasp the idea that counting plaques is essentially the same as counting viruses in their sample (assuming that one virus entering the cell is sufficient for productive infection), the process of plaque formation itself remains largely obscure. Many students fail to appreciate that viral plaques are actually a “laboratory-made” phenomenon allowing us to observe and study the growth of lytic viruses. The latter often presents a challenge for the interpretation of experimental data related to viral growth and drug discovery using plaque reduction assay. The hands-on model described here creates an opportunity for students to experience the process of viral plaque formation while engaging multiple senses and creating a lasting impression.Boriana MarintchevaAmerican Society for MicrobiologyarticleSpecial aspects of educationLC8-6691Biology (General)QH301-705.5ENJournal of Microbiology & Biology Education, Vol 13, Iss 2, Pp 186-187 (2012)
institution DOAJ
collection DOAJ
language EN
topic Special aspects of education
LC8-6691
Biology (General)
QH301-705.5
spellingShingle Special aspects of education
LC8-6691
Biology (General)
QH301-705.5
Boriana Marintcheva
Dynamic Model Visualizing the Process of Viral Plaque Formation
description In Microbiology and Virology courses, viral plaques are often presented to students as the way one can visualize viruses/bacteriophages. While students generally grasp the idea that counting plaques is essentially the same as counting viruses in their sample (assuming that one virus entering the cell is sufficient for productive infection), the process of plaque formation itself remains largely obscure. Many students fail to appreciate that viral plaques are actually a “laboratory-made” phenomenon allowing us to observe and study the growth of lytic viruses. The latter often presents a challenge for the interpretation of experimental data related to viral growth and drug discovery using plaque reduction assay. The hands-on model described here creates an opportunity for students to experience the process of viral plaque formation while engaging multiple senses and creating a lasting impression.
format article
author Boriana Marintcheva
author_facet Boriana Marintcheva
author_sort Boriana Marintcheva
title Dynamic Model Visualizing the Process of Viral Plaque Formation
title_short Dynamic Model Visualizing the Process of Viral Plaque Formation
title_full Dynamic Model Visualizing the Process of Viral Plaque Formation
title_fullStr Dynamic Model Visualizing the Process of Viral Plaque Formation
title_full_unstemmed Dynamic Model Visualizing the Process of Viral Plaque Formation
title_sort dynamic model visualizing the process of viral plaque formation
publisher American Society for Microbiology
publishDate 2012
url https://doaj.org/article/bdd8c6bb94744cf786118210f5730640
work_keys_str_mv AT borianamarintcheva dynamicmodelvisualizingtheprocessofviralplaqueformation
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