CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle
Gregorio, Colpan and Iwanski characterize the role of cyclase-associated protein 2 (CAP2) in regulating the organization and dynamics of actin filaments within cardiomyocytes. They show that CAP2 depolymerizes and inhibits actin incorporation into thin filaments and is also required for cardiomyocyt...
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| Main Authors: | , , |
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| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/bde9cd3dca6f4dd298abb535d9836f9b |
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| Summary: | Gregorio, Colpan and Iwanski characterize the role of cyclase-associated protein 2 (CAP2) in regulating the organization and dynamics of actin filaments within cardiomyocytes. They show that CAP2 depolymerizes and inhibits actin incorporation into thin filaments and is also required for cardiomyocyte maturation. |
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