CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle

Gregorio, Colpan and Iwanski characterize the role of cyclase-associated protein 2 (CAP2) in regulating the organization and dynamics of actin filaments within cardiomyocytes. They show that CAP2 depolymerizes and inhibits actin incorporation into thin filaments and is also required for cardiomyocyt...

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Autores principales: Mert Colpan, Jessika Iwanski, Carol C. Gregorio
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/bde9cd3dca6f4dd298abb535d9836f9b
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spelling oai:doaj.org-article:bde9cd3dca6f4dd298abb535d9836f9b2021-12-02T11:39:38ZCAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle10.1038/s42003-021-01893-w2399-3642https://doaj.org/article/bde9cd3dca6f4dd298abb535d9836f9b2021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01893-whttps://doaj.org/toc/2399-3642Gregorio, Colpan and Iwanski characterize the role of cyclase-associated protein 2 (CAP2) in regulating the organization and dynamics of actin filaments within cardiomyocytes. They show that CAP2 depolymerizes and inhibits actin incorporation into thin filaments and is also required for cardiomyocyte maturation.Mert ColpanJessika IwanskiCarol C. GregorioNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
institution DOAJ
collection DOAJ
language EN
topic Biology (General)
QH301-705.5
spellingShingle Biology (General)
QH301-705.5
Mert Colpan
Jessika Iwanski
Carol C. Gregorio
CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle
description Gregorio, Colpan and Iwanski characterize the role of cyclase-associated protein 2 (CAP2) in regulating the organization and dynamics of actin filaments within cardiomyocytes. They show that CAP2 depolymerizes and inhibits actin incorporation into thin filaments and is also required for cardiomyocyte maturation.
format article
author Mert Colpan
Jessika Iwanski
Carol C. Gregorio
author_facet Mert Colpan
Jessika Iwanski
Carol C. Gregorio
author_sort Mert Colpan
title CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle
title_short CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle
title_full CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle
title_fullStr CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle
title_full_unstemmed CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle
title_sort cap2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/bde9cd3dca6f4dd298abb535d9836f9b
work_keys_str_mv AT mertcolpan cap2isaregulatorofactinpointedenddynamicsandmyofibrillogenesisincardiacmuscle
AT jessikaiwanski cap2isaregulatorofactinpointedenddynamicsandmyofibrillogenesisincardiacmuscle
AT carolcgregorio cap2isaregulatorofactinpointedenddynamicsandmyofibrillogenesisincardiacmuscle
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