CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle
Gregorio, Colpan and Iwanski characterize the role of cyclase-associated protein 2 (CAP2) in regulating the organization and dynamics of actin filaments within cardiomyocytes. They show that CAP2 depolymerizes and inhibits actin incorporation into thin filaments and is also required for cardiomyocyt...
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Nature Portfolio
2021
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oai:doaj.org-article:bde9cd3dca6f4dd298abb535d9836f9b2021-12-02T11:39:38ZCAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle10.1038/s42003-021-01893-w2399-3642https://doaj.org/article/bde9cd3dca6f4dd298abb535d9836f9b2021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01893-whttps://doaj.org/toc/2399-3642Gregorio, Colpan and Iwanski characterize the role of cyclase-associated protein 2 (CAP2) in regulating the organization and dynamics of actin filaments within cardiomyocytes. They show that CAP2 depolymerizes and inhibits actin incorporation into thin filaments and is also required for cardiomyocyte maturation.Mert ColpanJessika IwanskiCarol C. GregorioNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-15 (2021) |
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DOAJ |
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EN |
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Biology (General) QH301-705.5 |
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Biology (General) QH301-705.5 Mert Colpan Jessika Iwanski Carol C. Gregorio CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle |
description |
Gregorio, Colpan and Iwanski characterize the role of cyclase-associated protein 2 (CAP2) in regulating the organization and dynamics of actin filaments within cardiomyocytes. They show that CAP2 depolymerizes and inhibits actin incorporation into thin filaments and is also required for cardiomyocyte maturation. |
format |
article |
author |
Mert Colpan Jessika Iwanski Carol C. Gregorio |
author_facet |
Mert Colpan Jessika Iwanski Carol C. Gregorio |
author_sort |
Mert Colpan |
title |
CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle |
title_short |
CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle |
title_full |
CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle |
title_fullStr |
CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle |
title_full_unstemmed |
CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle |
title_sort |
cap2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/bde9cd3dca6f4dd298abb535d9836f9b |
work_keys_str_mv |
AT mertcolpan cap2isaregulatorofactinpointedenddynamicsandmyofibrillogenesisincardiacmuscle AT jessikaiwanski cap2isaregulatorofactinpointedenddynamicsandmyofibrillogenesisincardiacmuscle AT carolcgregorio cap2isaregulatorofactinpointedenddynamicsandmyofibrillogenesisincardiacmuscle |
_version_ |
1718395723888721920 |