Demographic and genetic factors influence the abundance of infiltrating immune cells in human tissues

Immune infiltration provides critical information for health and disease, yet it is unclear what factors influence infiltration levels. Here, the authors analyze human tissue transcriptomes from the Genotype-Tissue Expression project to find infiltration patterns regulated by age, sex and host genet...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Andrew R. Marderstein, Manik Uppal, Akanksha Verma, Bhavneet Bhinder, Zakieh Tayyebi, Jason Mezey, Andrew G. Clark, Olivier Elemento
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bdf1df0cbfa4438ab46ff62705e1237e
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:bdf1df0cbfa4438ab46ff62705e1237e
record_format	dspace
spelling	oai:doaj.org-article:bdf1df0cbfa4438ab46ff62705e1237e2021-12-02T15:33:31ZDemographic and genetic factors influence the abundance of infiltrating immune cells in human tissues10.1038/s41467-020-16097-92041-1723https://doaj.org/article/bdf1df0cbfa4438ab46ff62705e1237e2020-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16097-9https://doaj.org/toc/2041-1723Immune infiltration provides critical information for health and disease, yet it is unclear what factors influence infiltration levels. Here, the authors analyze human tissue transcriptomes from the Genotype-Tissue Expression project to find infiltration patterns regulated by age, sex and host genetic information.Andrew R. MardersteinManik UppalAkanksha VermaBhavneet BhinderZakieh TayyebiJason MezeyAndrew G. ClarkOlivier ElementoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Andrew R. Marderstein Manik Uppal Akanksha Verma Bhavneet Bhinder Zakieh Tayyebi Jason Mezey Andrew G. Clark Olivier Elemento Demographic and genetic factors influence the abundance of infiltrating immune cells in human tissues
description	Immune infiltration provides critical information for health and disease, yet it is unclear what factors influence infiltration levels. Here, the authors analyze human tissue transcriptomes from the Genotype-Tissue Expression project to find infiltration patterns regulated by age, sex and host genetic information.
format	article
author	Andrew R. Marderstein Manik Uppal Akanksha Verma Bhavneet Bhinder Zakieh Tayyebi Jason Mezey Andrew G. Clark Olivier Elemento
author_facet	Andrew R. Marderstein Manik Uppal Akanksha Verma Bhavneet Bhinder Zakieh Tayyebi Jason Mezey Andrew G. Clark Olivier Elemento
author_sort	Andrew R. Marderstein
title	Demographic and genetic factors influence the abundance of infiltrating immune cells in human tissues
title_short	Demographic and genetic factors influence the abundance of infiltrating immune cells in human tissues
title_full	Demographic and genetic factors influence the abundance of infiltrating immune cells in human tissues
title_fullStr	Demographic and genetic factors influence the abundance of infiltrating immune cells in human tissues
title_full_unstemmed	Demographic and genetic factors influence the abundance of infiltrating immune cells in human tissues
title_sort	demographic and genetic factors influence the abundance of infiltrating immune cells in human tissues
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/bdf1df0cbfa4438ab46ff62705e1237e
work_keys_str_mv	AT andrewrmarderstein demographicandgeneticfactorsinfluencetheabundanceofinfiltratingimmunecellsinhumantissues AT manikuppal demographicandgeneticfactorsinfluencetheabundanceofinfiltratingimmunecellsinhumantissues AT akankshaverma demographicandgeneticfactorsinfluencetheabundanceofinfiltratingimmunecellsinhumantissues AT bhavneetbhinder demographicandgeneticfactorsinfluencetheabundanceofinfiltratingimmunecellsinhumantissues AT zakiehtayyebi demographicandgeneticfactorsinfluencetheabundanceofinfiltratingimmunecellsinhumantissues AT jasonmezey demographicandgeneticfactorsinfluencetheabundanceofinfiltratingimmunecellsinhumantissues AT andrewgclark demographicandgeneticfactorsinfluencetheabundanceofinfiltratingimmunecellsinhumantissues AT olivierelemento demographicandgeneticfactorsinfluencetheabundanceofinfiltratingimmunecellsinhumantissues
_version_	1718387104341295104

Demographic and genetic factors influence the abundance of infiltrating immune cells in human tissues

Ejemplares similares