COVID-19 ARDS: Points to Be Considered in Mechanical Ventilation and Weaning

The COVID-19 disease can cause hypoxemic respiratory failure due to ARDS, requiring invasive mechanical ventilation. Although early studies reported that COVID-19-associated ARDS has distinctive features from ARDS of other causes, recent observational studies have demonstrated that ARDS related to C...

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Autores principales:	Eumorfia Kondili, Demosthenes Makris, Dimitrios Georgopoulos, Nikoletta Rovina, Anastasia Kotanidou, Antonia Koutsoukou
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	COVID-19 lung injury mechanical ventilation weaning Medicine R
Acceso en línea:	https://doaj.org/article/bdfcc4ad019b43a9b92ea417d4a9931b
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spelling	oai:doaj.org-article:bdfcc4ad019b43a9b92ea417d4a9931b2021-11-25T18:07:16ZCOVID-19 ARDS: Points to Be Considered in Mechanical Ventilation and Weaning10.3390/jpm111111092075-4426https://doaj.org/article/bdfcc4ad019b43a9b92ea417d4a9931b2021-10-01T00:00:00Zhttps://www.mdpi.com/2075-4426/11/11/1109https://doaj.org/toc/2075-4426The COVID-19 disease can cause hypoxemic respiratory failure due to ARDS, requiring invasive mechanical ventilation. Although early studies reported that COVID-19-associated ARDS has distinctive features from ARDS of other causes, recent observational studies have demonstrated that ARDS related to COVID-19 shares common clinical characteristics and respiratory system mechanics with ARDS of other origins. Therefore, mechanical ventilation in these patients should be based on strategies aiming to mitigate ventilator-induced lung injury. Assisted mechanical ventilation should be applied early in the course of mechanical ventilation by considering evaluation and minimizing factors associated with patient-inflicted lung injury. Extracorporeal membrane oxygenation should be considered in selected patients with refractory hypoxia not responding to conventional ventilation strategies. This review highlights the current and evolving practice in managing mechanically ventilated patients with ARDS related to COVID-19.Eumorfia KondiliDemosthenes MakrisDimitrios GeorgopoulosNikoletta RovinaAnastasia KotanidouAntonia KoutsoukouMDPI AGarticleCOVID-19lung injurymechanical ventilationweaningMedicineRENJournal of Personalized Medicine, Vol 11, Iss 1109, p 1109 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	COVID-19 lung injury mechanical ventilation weaning Medicine R
spellingShingle	COVID-19 lung injury mechanical ventilation weaning Medicine R Eumorfia Kondili Demosthenes Makris Dimitrios Georgopoulos Nikoletta Rovina Anastasia Kotanidou Antonia Koutsoukou COVID-19 ARDS: Points to Be Considered in Mechanical Ventilation and Weaning
description	The COVID-19 disease can cause hypoxemic respiratory failure due to ARDS, requiring invasive mechanical ventilation. Although early studies reported that COVID-19-associated ARDS has distinctive features from ARDS of other causes, recent observational studies have demonstrated that ARDS related to COVID-19 shares common clinical characteristics and respiratory system mechanics with ARDS of other origins. Therefore, mechanical ventilation in these patients should be based on strategies aiming to mitigate ventilator-induced lung injury. Assisted mechanical ventilation should be applied early in the course of mechanical ventilation by considering evaluation and minimizing factors associated with patient-inflicted lung injury. Extracorporeal membrane oxygenation should be considered in selected patients with refractory hypoxia not responding to conventional ventilation strategies. This review highlights the current and evolving practice in managing mechanically ventilated patients with ARDS related to COVID-19.
format	article
author	Eumorfia Kondili Demosthenes Makris Dimitrios Georgopoulos Nikoletta Rovina Anastasia Kotanidou Antonia Koutsoukou
author_facet	Eumorfia Kondili Demosthenes Makris Dimitrios Georgopoulos Nikoletta Rovina Anastasia Kotanidou Antonia Koutsoukou
author_sort	Eumorfia Kondili
title	COVID-19 ARDS: Points to Be Considered in Mechanical Ventilation and Weaning
title_short	COVID-19 ARDS: Points to Be Considered in Mechanical Ventilation and Weaning
title_full	COVID-19 ARDS: Points to Be Considered in Mechanical Ventilation and Weaning
title_fullStr	COVID-19 ARDS: Points to Be Considered in Mechanical Ventilation and Weaning
title_full_unstemmed	COVID-19 ARDS: Points to Be Considered in Mechanical Ventilation and Weaning
title_sort	covid-19 ards: points to be considered in mechanical ventilation and weaning
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/bdfcc4ad019b43a9b92ea417d4a9931b
work_keys_str_mv	AT eumorfiakondili covid19ardspointstobeconsideredinmechanicalventilationandweaning AT demosthenesmakris covid19ardspointstobeconsideredinmechanicalventilationandweaning AT dimitriosgeorgopoulos covid19ardspointstobeconsideredinmechanicalventilationandweaning AT nikolettarovina covid19ardspointstobeconsideredinmechanicalventilationandweaning AT anastasiakotanidou covid19ardspointstobeconsideredinmechanicalventilationandweaning AT antoniakoutsoukou covid19ardspointstobeconsideredinmechanicalventilationandweaning
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COVID-19 ARDS: Points to Be Considered in Mechanical Ventilation and Weaning

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