Cardiac troponin I in non- acute coronary syndrome patients with chronic kidney disease.

<h4>Objective</h4>The aim of this study was to assess the results of troponin I (cTnI) in non- acute Coronary Syndrome (ACS) patients with chronic kidney disease (CKD). We also examined the risk factors for elevated cTnI in non-ACS patients with CKD and whether stage 5 CKD modifies the a...

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Autores principales:	Shanying Chen, Chunhong Huang, Bide Wu, Xuejian Lian, Xuqiao Mei, Jianxin Wan
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/be04c735915f4002b9730ba6e6907084
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spelling	oai:doaj.org-article:be04c735915f4002b9730ba6e69070842021-11-18T08:42:12ZCardiac troponin I in non- acute coronary syndrome patients with chronic kidney disease.1932-620310.1371/journal.pone.0082752https://doaj.org/article/be04c735915f4002b9730ba6e69070842013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24349354/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Objective</h4>The aim of this study was to assess the results of troponin I (cTnI) in non- acute Coronary Syndrome (ACS) patients with chronic kidney disease (CKD). We also examined the risk factors for elevated cTnI in non-ACS patients with CKD and whether stage 5 CKD modifies the associations of elevated cTnI and the risk factors in non-ACS patients with CKD.<h4>Methods</h4>A retrospective study was performed. Logistic regression models were used.<h4>Results</h4>293 non-ACS patients with CKD were included in the current study. 43.34% non-ACS patients with CKD have an elevated cTnI level and 5.12% have an elevated cTnT level in MI range. In CKD patients without ACS and heart failure, only 26.03% (38/146) patients have an elevated cTnT level. In adjusted analyses, age, diastolic blood pressure and congestive heart failure is associated with an elevated cTnI level in non-ACS patients with CKD. Congestive heart failure is associated with an elevated cTnI level in non-ACS patients with CKD (OR 2.30, 95% CI 1.08,4.88, P=0.03). Stage 5 CKD does not modify the association of congestive heart failure and an elevated cTnI level.<h4>Conclusion</h4>43.34% non-ACS patients with CKD and 26.03% CKD patients without ACS and congestive heart failure have an elevated cTnI level. Congestive heart failure is associated with an elevated cTnI level in non-ACS patients with CKD. Stage 5 CKD does not modify the association of congestive heart failure and an elevated cTnI level.Shanying ChenChunhong HuangBide WuXuejian LianXuqiao MeiJianxin WanPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 8, Iss 12, p e82752 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Shanying Chen Chunhong Huang Bide Wu Xuejian Lian Xuqiao Mei Jianxin Wan Cardiac troponin I in non- acute coronary syndrome patients with chronic kidney disease.
description	<h4>Objective</h4>The aim of this study was to assess the results of troponin I (cTnI) in non- acute Coronary Syndrome (ACS) patients with chronic kidney disease (CKD). We also examined the risk factors for elevated cTnI in non-ACS patients with CKD and whether stage 5 CKD modifies the associations of elevated cTnI and the risk factors in non-ACS patients with CKD.<h4>Methods</h4>A retrospective study was performed. Logistic regression models were used.<h4>Results</h4>293 non-ACS patients with CKD were included in the current study. 43.34% non-ACS patients with CKD have an elevated cTnI level and 5.12% have an elevated cTnT level in MI range. In CKD patients without ACS and heart failure, only 26.03% (38/146) patients have an elevated cTnT level. In adjusted analyses, age, diastolic blood pressure and congestive heart failure is associated with an elevated cTnI level in non-ACS patients with CKD. Congestive heart failure is associated with an elevated cTnI level in non-ACS patients with CKD (OR 2.30, 95% CI 1.08,4.88, P=0.03). Stage 5 CKD does not modify the association of congestive heart failure and an elevated cTnI level.<h4>Conclusion</h4>43.34% non-ACS patients with CKD and 26.03% CKD patients without ACS and congestive heart failure have an elevated cTnI level. Congestive heart failure is associated with an elevated cTnI level in non-ACS patients with CKD. Stage 5 CKD does not modify the association of congestive heart failure and an elevated cTnI level.
format	article
author	Shanying Chen Chunhong Huang Bide Wu Xuejian Lian Xuqiao Mei Jianxin Wan
author_facet	Shanying Chen Chunhong Huang Bide Wu Xuejian Lian Xuqiao Mei Jianxin Wan
author_sort	Shanying Chen
title	Cardiac troponin I in non- acute coronary syndrome patients with chronic kidney disease.
title_short	Cardiac troponin I in non- acute coronary syndrome patients with chronic kidney disease.
title_full	Cardiac troponin I in non- acute coronary syndrome patients with chronic kidney disease.
title_fullStr	Cardiac troponin I in non- acute coronary syndrome patients with chronic kidney disease.
title_full_unstemmed	Cardiac troponin I in non- acute coronary syndrome patients with chronic kidney disease.
title_sort	cardiac troponin i in non- acute coronary syndrome patients with chronic kidney disease.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/be04c735915f4002b9730ba6e6907084
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Cardiac troponin I in non- acute coronary syndrome patients with chronic kidney disease.

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