INVOLVEMENT OF PERFORIN/GRANZYME B-DEPENDENT SIGNALING PATHWAY IN CYTOTOXIC ACTIVITY OF DENDRITIC CELLS TOWARDS HUMAN GLIOBLASTOMA CELLS

Granule-mediated cytotoxicity of effector cells is a universal mechanism of tumor growth inhibition and induction of tumor cell death. The aim of present  study was to evaluate  expression  of lytic molecules in DCs generated in presence of IFNα (IFN-DCs), and to analyze  the role of granule-mediate...

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Autores principales: T. V. Tyrinova, O. Yu. Leplina, S. V. Mishinov, M. A. Tikhonova, A. V. Kalinovskiy, S. V. Chernov, V. V. Stupak, A. A. Ostanin, E. R. Chernykh
Formato: article
Lenguaje:RU
Publicado: SPb RAACI 2017
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Acceso en línea:https://doaj.org/article/be14d1acae6b465cab41685b8703bd80
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