Assessing the impact of imperfect adherence to artemether-lumefantrine on malaria treatment outcomes using within-host modelling

Artemether lumefantrine is widely used for the treatment of uncomplicated malaria. The impact of imperfect patient adherence to the six-dose regimen is hard to assess. Using adherence data for unsupervised patients, the authors model how suboptimal adherence affects treatment outcomes.

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Detalles Bibliográficos
Autores principales:	Joseph D. Challenger, Katia Bruxvoort, Azra C. Ghani, Lucy C. Okell
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/be1a2b6957f54156a4adac50845795aa
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spelling	oai:doaj.org-article:be1a2b6957f54156a4adac50845795aa2021-12-02T17:01:18ZAssessing the impact of imperfect adherence to artemether-lumefantrine on malaria treatment outcomes using within-host modelling10.1038/s41467-017-01352-32041-1723https://doaj.org/article/be1a2b6957f54156a4adac50845795aa2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01352-3https://doaj.org/toc/2041-1723Artemether lumefantrine is widely used for the treatment of uncomplicated malaria. The impact of imperfect patient adherence to the six-dose regimen is hard to assess. Using adherence data for unsupervised patients, the authors model how suboptimal adherence affects treatment outcomes.Joseph D. ChallengerKatia BruxvoortAzra C. GhaniLucy C. OkellNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Joseph D. Challenger Katia Bruxvoort Azra C. Ghani Lucy C. Okell Assessing the impact of imperfect adherence to artemether-lumefantrine on malaria treatment outcomes using within-host modelling
description	Artemether lumefantrine is widely used for the treatment of uncomplicated malaria. The impact of imperfect patient adherence to the six-dose regimen is hard to assess. Using adherence data for unsupervised patients, the authors model how suboptimal adherence affects treatment outcomes.
format	article
author	Joseph D. Challenger Katia Bruxvoort Azra C. Ghani Lucy C. Okell
author_facet	Joseph D. Challenger Katia Bruxvoort Azra C. Ghani Lucy C. Okell
author_sort	Joseph D. Challenger
title	Assessing the impact of imperfect adherence to artemether-lumefantrine on malaria treatment outcomes using within-host modelling
title_short	Assessing the impact of imperfect adherence to artemether-lumefantrine on malaria treatment outcomes using within-host modelling
title_full	Assessing the impact of imperfect adherence to artemether-lumefantrine on malaria treatment outcomes using within-host modelling
title_fullStr	Assessing the impact of imperfect adherence to artemether-lumefantrine on malaria treatment outcomes using within-host modelling
title_full_unstemmed	Assessing the impact of imperfect adherence to artemether-lumefantrine on malaria treatment outcomes using within-host modelling
title_sort	assessing the impact of imperfect adherence to artemether-lumefantrine on malaria treatment outcomes using within-host modelling
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/be1a2b6957f54156a4adac50845795aa
work_keys_str_mv	AT josephdchallenger assessingtheimpactofimperfectadherencetoartemetherlumefantrineonmalariatreatmentoutcomesusingwithinhostmodelling AT katiabruxvoort assessingtheimpactofimperfectadherencetoartemetherlumefantrineonmalariatreatmentoutcomesusingwithinhostmodelling AT azracghani assessingtheimpactofimperfectadherencetoartemetherlumefantrineonmalariatreatmentoutcomesusingwithinhostmodelling AT lucycokell assessingtheimpactofimperfectadherencetoartemetherlumefantrineonmalariatreatmentoutcomesusingwithinhostmodelling
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Assessing the impact of imperfect adherence to artemether-lumefantrine on malaria treatment outcomes using within-host modelling

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