Structure of the p53/RNA polymerase II assembly
Liou et al. report a 4.6 Å resolution structure of the human p53/ RNA polymerase II assembly, using single particle cryoelectron microscopy. This study suggests that p53’s functional domains regulate the DNA binding activity of RNA polymerase II, providing insights into p53-regulated gene expression...
Guardado en:
Autores principales: | Shu-Hao Liou, Sameer K. Singh, Robert H. Singer, Robert A. Coleman, Wei-Li Liu |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/be1a87333b6a4982b660b7ba76442e68 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Evolution of complex RNA polymerases: the complete archaeal RNA polymerase structure.
por: Yakov Korkhin, et al.
Publicado: (2009) -
Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2
por: Isaac Fianu, et al.
Publicado: (2021) -
Complete structural model of Escherichia coli RNA polymerase from a hybrid approach.
por: Natacha Opalka, et al.
Publicado: (2010) -
The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing.
por: Yehuda Brody, et al.
Publicado: (2011) -
The Δ40p53 isoform inhibits p53-dependent eRNA transcription and enables regulation by signal-specific transcription factors during p53 activation.
por: Cecilia B Levandowski, et al.
Publicado: (2021)