The crystal structures of dystrophin and utrophin spectrin repeats: implications for domain boundaries.
Dystrophin and utrophin link the F-actin cytoskeleton to the cell membrane via an associated glycoprotein complex. This functionality results from their domain organization having an N-terminal actin-binding domain followed by multiple spectrin-repeat domains and then C-terminal protein-binding moti...
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Main Authors: | Muralidharan Muthu, Kylie A Richardson, Andrew J Sutherland-Smith |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2012
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Online Access: | https://doaj.org/article/be27e30badbe48c4aa5a01ec92a60f4a |
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