Real-world data from a molecular tumor board demonstrates improved outcomes with a precision N-of-One strategy

A molecular tumor board (MTB) is often used as a platform that integrates clinical and molecular parameters for clinical decision making. Here, the authors review the outcome of 715 cancer patients presented at their institution’s MTB, and demonstrate that patients who received a MTB-recommended reg...

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Autores principales:	Shumei Kato, Ki Hwan Kim, Hyo Jeong Lim, Amelie Boichard, Mina Nikanjam, Elizabeth Weihe, Dennis J. Kuo, Ramez N. Eskander, Aaron Goodman, Natalie Galanina, Paul T. Fanta, Richard B. Schwab, Rebecca Shatsky, Steven C. Plaxe, Andrew Sharabi, Edward Stites, Jacob J. Adashek, Ryosuke Okamura, Suzanna Lee, Scott M. Lippman, Jason K. Sicklick, Razelle Kurzrock
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/be2daa0bb1884adbb304041e571d8edf
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spelling	oai:doaj.org-article:be2daa0bb1884adbb304041e571d8edf2021-12-02T19:16:55ZReal-world data from a molecular tumor board demonstrates improved outcomes with a precision N-of-One strategy10.1038/s41467-020-18613-32041-1723https://doaj.org/article/be2daa0bb1884adbb304041e571d8edf2020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18613-3https://doaj.org/toc/2041-1723A molecular tumor board (MTB) is often used as a platform that integrates clinical and molecular parameters for clinical decision making. Here, the authors review the outcome of 715 cancer patients presented at their institution’s MTB, and demonstrate that patients who received a MTB-recommended regimen received therapy that was better matched to their alterations and achieved better clinical outcomes.Shumei KatoKi Hwan KimHyo Jeong LimAmelie BoichardMina NikanjamElizabeth WeiheDennis J. KuoRamez N. EskanderAaron GoodmanNatalie GalaninaPaul T. FantaRichard B. SchwabRebecca ShatskySteven C. PlaxeAndrew SharabiEdward StitesJacob J. AdashekRyosuke OkamuraSuzanna LeeScott M. LippmanJason K. SicklickRazelle KurzrockNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shumei Kato Ki Hwan Kim Hyo Jeong Lim Amelie Boichard Mina Nikanjam Elizabeth Weihe Dennis J. Kuo Ramez N. Eskander Aaron Goodman Natalie Galanina Paul T. Fanta Richard B. Schwab Rebecca Shatsky Steven C. Plaxe Andrew Sharabi Edward Stites Jacob J. Adashek Ryosuke Okamura Suzanna Lee Scott M. Lippman Jason K. Sicklick Razelle Kurzrock Real-world data from a molecular tumor board demonstrates improved outcomes with a precision N-of-One strategy
description	A molecular tumor board (MTB) is often used as a platform that integrates clinical and molecular parameters for clinical decision making. Here, the authors review the outcome of 715 cancer patients presented at their institution’s MTB, and demonstrate that patients who received a MTB-recommended regimen received therapy that was better matched to their alterations and achieved better clinical outcomes.
format	article
author	Shumei Kato Ki Hwan Kim Hyo Jeong Lim Amelie Boichard Mina Nikanjam Elizabeth Weihe Dennis J. Kuo Ramez N. Eskander Aaron Goodman Natalie Galanina Paul T. Fanta Richard B. Schwab Rebecca Shatsky Steven C. Plaxe Andrew Sharabi Edward Stites Jacob J. Adashek Ryosuke Okamura Suzanna Lee Scott M. Lippman Jason K. Sicklick Razelle Kurzrock
author_facet	Shumei Kato Ki Hwan Kim Hyo Jeong Lim Amelie Boichard Mina Nikanjam Elizabeth Weihe Dennis J. Kuo Ramez N. Eskander Aaron Goodman Natalie Galanina Paul T. Fanta Richard B. Schwab Rebecca Shatsky Steven C. Plaxe Andrew Sharabi Edward Stites Jacob J. Adashek Ryosuke Okamura Suzanna Lee Scott M. Lippman Jason K. Sicklick Razelle Kurzrock
author_sort	Shumei Kato
title	Real-world data from a molecular tumor board demonstrates improved outcomes with a precision N-of-One strategy
title_short	Real-world data from a molecular tumor board demonstrates improved outcomes with a precision N-of-One strategy
title_full	Real-world data from a molecular tumor board demonstrates improved outcomes with a precision N-of-One strategy
title_fullStr	Real-world data from a molecular tumor board demonstrates improved outcomes with a precision N-of-One strategy
title_full_unstemmed	Real-world data from a molecular tumor board demonstrates improved outcomes with a precision N-of-One strategy
title_sort	real-world data from a molecular tumor board demonstrates improved outcomes with a precision n-of-one strategy
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/be2daa0bb1884adbb304041e571d8edf
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Real-world data from a molecular tumor board demonstrates improved outcomes with a precision N-of-One strategy

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