Destination Therapy with Left Ventricular Assist Devices in Non-transplant Centres: The Time is Right

For almost half a century, cardiac transplant has been the only long-term treatment for patients with end-stage heart failure. Implantable left ventricular assist devices (LVADs) have emerged as a new treatment option for advanced heart failure as destination therapy for patients either too old or n...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Antoni Bayes-Genis, Christian Muñoz-Guijosa, Evelyn Santiago-Vacas, Santiago Montero, Cosme García-García, Pau Codina, Julio Núñez, Josep Lupón
Formato:	article
Lenguaje:	EN
Publicado:	Radcliffe Medical Media 2020
Materias:	Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/be4155e7d29f46fea89718127ee72f06
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:be4155e7d29f46fea89718127ee72f06
record_format	dspace
spelling	oai:doaj.org-article:be4155e7d29f46fea89718127ee72f062021-12-04T16:02:37ZDestination Therapy with Left Ventricular Assist Devices in Non-transplant Centres: The Time is Right10.15420/ecr.2019.29.21758-37641758-3756https://doaj.org/article/be4155e7d29f46fea89718127ee72f062020-04-01T00:00:00Zhttps://www.ecrjournal.com/articleindex/ecr.2019.29.2https://doaj.org/toc/1758-3756https://doaj.org/toc/1758-3764For almost half a century, cardiac transplant has been the only long-term treatment for patients with end-stage heart failure. Implantable left ventricular assist devices (LVADs) have emerged as a new treatment option for advanced heart failure as destination therapy for patients either too old or not suitable for transplant. A meta-analysis presenting head-to-head comparisons of cardiac transplant versus LVAD as destination therapy (LVAD-DT) found no difference in 1-year mortality rates between LVAD-DT and cardiac transplant (OR 1.49; 95% CI [0.48–4.66]; I2=82.8%). Moreover, a recent subanalysis from the Interagency Registry for Mechanically Assisted Circulatory Support found similar outcomes after LVAD-DT implantation in both transplant and non-transplant centres. The time is right for LVAD-DT in non-transplant centres, provided multidisciplinary heart failure teams and expertise are in place.Antoni Bayes-GenisChristian Muñoz-GuijosaEvelyn Santiago-VacasSantiago MonteroCosme García-GarcíaPau CodinaJulio NúñezJosep LupónRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENEuropean Cardiology Review , Vol 15, Iss , Pp - (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	Diseases of the circulatory (Cardiovascular) system RC666-701 Antoni Bayes-Genis Christian Muñoz-Guijosa Evelyn Santiago-Vacas Santiago Montero Cosme García-García Pau Codina Julio Núñez Josep Lupón Destination Therapy with Left Ventricular Assist Devices in Non-transplant Centres: The Time is Right
description	For almost half a century, cardiac transplant has been the only long-term treatment for patients with end-stage heart failure. Implantable left ventricular assist devices (LVADs) have emerged as a new treatment option for advanced heart failure as destination therapy for patients either too old or not suitable for transplant. A meta-analysis presenting head-to-head comparisons of cardiac transplant versus LVAD as destination therapy (LVAD-DT) found no difference in 1-year mortality rates between LVAD-DT and cardiac transplant (OR 1.49; 95% CI [0.48–4.66]; I2=82.8%). Moreover, a recent subanalysis from the Interagency Registry for Mechanically Assisted Circulatory Support found similar outcomes after LVAD-DT implantation in both transplant and non-transplant centres. The time is right for LVAD-DT in non-transplant centres, provided multidisciplinary heart failure teams and expertise are in place.
format	article
author	Antoni Bayes-Genis Christian Muñoz-Guijosa Evelyn Santiago-Vacas Santiago Montero Cosme García-García Pau Codina Julio Núñez Josep Lupón
author_facet	Antoni Bayes-Genis Christian Muñoz-Guijosa Evelyn Santiago-Vacas Santiago Montero Cosme García-García Pau Codina Julio Núñez Josep Lupón
author_sort	Antoni Bayes-Genis
title	Destination Therapy with Left Ventricular Assist Devices in Non-transplant Centres: The Time is Right
title_short	Destination Therapy with Left Ventricular Assist Devices in Non-transplant Centres: The Time is Right
title_full	Destination Therapy with Left Ventricular Assist Devices in Non-transplant Centres: The Time is Right
title_fullStr	Destination Therapy with Left Ventricular Assist Devices in Non-transplant Centres: The Time is Right
title_full_unstemmed	Destination Therapy with Left Ventricular Assist Devices in Non-transplant Centres: The Time is Right
title_sort	destination therapy with left ventricular assist devices in non-transplant centres: the time is right
publisher	Radcliffe Medical Media
publishDate	2020
url	https://doaj.org/article/be4155e7d29f46fea89718127ee72f06
work_keys_str_mv	AT antonibayesgenis destinationtherapywithleftventricularassistdevicesinnontransplantcentresthetimeisright AT christianmunozguijosa destinationtherapywithleftventricularassistdevicesinnontransplantcentresthetimeisright AT evelynsantiagovacas destinationtherapywithleftventricularassistdevicesinnontransplantcentresthetimeisright AT santiagomontero destinationtherapywithleftventricularassistdevicesinnontransplantcentresthetimeisright AT cosmegarciagarcia destinationtherapywithleftventricularassistdevicesinnontransplantcentresthetimeisright AT paucodina destinationtherapywithleftventricularassistdevicesinnontransplantcentresthetimeisright AT julionunez destinationtherapywithleftventricularassistdevicesinnontransplantcentresthetimeisright AT joseplupon destinationtherapywithleftventricularassistdevicesinnontransplantcentresthetimeisright
_version_	1718372757224292352

Destination Therapy with Left Ventricular Assist Devices in Non-transplant Centres: The Time is Right

Ejemplares similares