TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis

TWEAK is a TNF family member that binds the NFκB signalling receptor Fn14. Here the authors show that TWEAK is central to skin inflammation in mouse models of atopic dermatitis and psoriasis and causes similar pathology when injected subcutaneously into mice.

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Autores principales: Daniel Sidler, Ping Wu, Rana Herro, Meike Claus, Dennis Wolf, Yuko Kawakami, Toshiaki Kawakami, Linda Burkly, Michael Croft
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/be41c55c70374481a6ffc5f13f861470
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spelling oai:doaj.org-article:be41c55c70374481a6ffc5f13f8614702021-12-02T14:42:43ZTWEAK mediates inflammation in experimental atopic dermatitis and psoriasis10.1038/ncomms153952041-1723https://doaj.org/article/be41c55c70374481a6ffc5f13f8614702017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15395https://doaj.org/toc/2041-1723TWEAK is a TNF family member that binds the NFκB signalling receptor Fn14. Here the authors show that TWEAK is central to skin inflammation in mouse models of atopic dermatitis and psoriasis and causes similar pathology when injected subcutaneously into mice.Daniel SidlerPing WuRana HerroMeike ClausDennis WolfYuko KawakamiToshiaki KawakamiLinda BurklyMichael CroftNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Daniel Sidler
Ping Wu
Rana Herro
Meike Claus
Dennis Wolf
Yuko Kawakami
Toshiaki Kawakami
Linda Burkly
Michael Croft
TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis
description TWEAK is a TNF family member that binds the NFκB signalling receptor Fn14. Here the authors show that TWEAK is central to skin inflammation in mouse models of atopic dermatitis and psoriasis and causes similar pathology when injected subcutaneously into mice.
format article
author Daniel Sidler
Ping Wu
Rana Herro
Meike Claus
Dennis Wolf
Yuko Kawakami
Toshiaki Kawakami
Linda Burkly
Michael Croft
author_facet Daniel Sidler
Ping Wu
Rana Herro
Meike Claus
Dennis Wolf
Yuko Kawakami
Toshiaki Kawakami
Linda Burkly
Michael Croft
author_sort Daniel Sidler
title TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis
title_short TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis
title_full TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis
title_fullStr TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis
title_full_unstemmed TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis
title_sort tweak mediates inflammation in experimental atopic dermatitis and psoriasis
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/be41c55c70374481a6ffc5f13f861470
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AT michaelcroft tweakmediatesinflammationinexperimentalatopicdermatitisandpsoriasis
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