TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis
TWEAK is a TNF family member that binds the NFκB signalling receptor Fn14. Here the authors show that TWEAK is central to skin inflammation in mouse models of atopic dermatitis and psoriasis and causes similar pathology when injected subcutaneously into mice.
Guardado en:
Autores principales: | , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2017
|
Materias: | |
Acceso en línea: | https://doaj.org/article/be41c55c70374481a6ffc5f13f861470 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:be41c55c70374481a6ffc5f13f861470 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:be41c55c70374481a6ffc5f13f8614702021-12-02T14:42:43ZTWEAK mediates inflammation in experimental atopic dermatitis and psoriasis10.1038/ncomms153952041-1723https://doaj.org/article/be41c55c70374481a6ffc5f13f8614702017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15395https://doaj.org/toc/2041-1723TWEAK is a TNF family member that binds the NFκB signalling receptor Fn14. Here the authors show that TWEAK is central to skin inflammation in mouse models of atopic dermatitis and psoriasis and causes similar pathology when injected subcutaneously into mice.Daniel SidlerPing WuRana HerroMeike ClausDennis WolfYuko KawakamiToshiaki KawakamiLinda BurklyMichael CroftNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Daniel Sidler Ping Wu Rana Herro Meike Claus Dennis Wolf Yuko Kawakami Toshiaki Kawakami Linda Burkly Michael Croft TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis |
description |
TWEAK is a TNF family member that binds the NFκB signalling receptor Fn14. Here the authors show that TWEAK is central to skin inflammation in mouse models of atopic dermatitis and psoriasis and causes similar pathology when injected subcutaneously into mice. |
format |
article |
author |
Daniel Sidler Ping Wu Rana Herro Meike Claus Dennis Wolf Yuko Kawakami Toshiaki Kawakami Linda Burkly Michael Croft |
author_facet |
Daniel Sidler Ping Wu Rana Herro Meike Claus Dennis Wolf Yuko Kawakami Toshiaki Kawakami Linda Burkly Michael Croft |
author_sort |
Daniel Sidler |
title |
TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis |
title_short |
TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis |
title_full |
TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis |
title_fullStr |
TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis |
title_full_unstemmed |
TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis |
title_sort |
tweak mediates inflammation in experimental atopic dermatitis and psoriasis |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/be41c55c70374481a6ffc5f13f861470 |
work_keys_str_mv |
AT danielsidler tweakmediatesinflammationinexperimentalatopicdermatitisandpsoriasis AT pingwu tweakmediatesinflammationinexperimentalatopicdermatitisandpsoriasis AT ranaherro tweakmediatesinflammationinexperimentalatopicdermatitisandpsoriasis AT meikeclaus tweakmediatesinflammationinexperimentalatopicdermatitisandpsoriasis AT denniswolf tweakmediatesinflammationinexperimentalatopicdermatitisandpsoriasis AT yukokawakami tweakmediatesinflammationinexperimentalatopicdermatitisandpsoriasis AT toshiakikawakami tweakmediatesinflammationinexperimentalatopicdermatitisandpsoriasis AT lindaburkly tweakmediatesinflammationinexperimentalatopicdermatitisandpsoriasis AT michaelcroft tweakmediatesinflammationinexperimentalatopicdermatitisandpsoriasis |
_version_ |
1718389656240783360 |