Flux of signalling endosomes undergoing axonal retrograde transport is encoded by presynaptic activity and TrkB

Signalling endosomes are known to be essential for neuronal survival. Here the authors show that, in cultured hippocampal neurons and live Drosophilalarval motor neurons, neuronal activity increases the retrograde flux of signalling endosomes, and this coupling depends on TrkB activation.

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Autores principales:	Tong Wang, Sally Martin, Tam H. Nguyen, Callista B. Harper, Rachel S. Gormal, Ramon Martínez-Mármol, Shanker Karunanithi, Elizabeth J. Coulson, Nick R. Glass, Justin J. Cooper-White, Bruno van Swinderen, Frédéric A. Meunier
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/be42e86f725a40bf81556fbeac83c206
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spelling	oai:doaj.org-article:be42e86f725a40bf81556fbeac83c2062021-12-02T14:38:35ZFlux of signalling endosomes undergoing axonal retrograde transport is encoded by presynaptic activity and TrkB10.1038/ncomms129762041-1723https://doaj.org/article/be42e86f725a40bf81556fbeac83c2062016-09-01T00:00:00Zhttps://doi.org/10.1038/ncomms12976https://doaj.org/toc/2041-1723Signalling endosomes are known to be essential for neuronal survival. Here the authors show that, in cultured hippocampal neurons and live Drosophilalarval motor neurons, neuronal activity increases the retrograde flux of signalling endosomes, and this coupling depends on TrkB activation.Tong WangSally MartinTam H. NguyenCallista B. HarperRachel S. GormalRamon Martínez-MármolShanker KarunanithiElizabeth J. CoulsonNick R. GlassJustin J. Cooper-WhiteBruno van SwinderenFrédéric A. MeunierNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Tong Wang Sally Martin Tam H. Nguyen Callista B. Harper Rachel S. Gormal Ramon Martínez-Mármol Shanker Karunanithi Elizabeth J. Coulson Nick R. Glass Justin J. Cooper-White Bruno van Swinderen Frédéric A. Meunier Flux of signalling endosomes undergoing axonal retrograde transport is encoded by presynaptic activity and TrkB
description	Signalling endosomes are known to be essential for neuronal survival. Here the authors show that, in cultured hippocampal neurons and live Drosophilalarval motor neurons, neuronal activity increases the retrograde flux of signalling endosomes, and this coupling depends on TrkB activation.
format	article
author	Tong Wang Sally Martin Tam H. Nguyen Callista B. Harper Rachel S. Gormal Ramon Martínez-Mármol Shanker Karunanithi Elizabeth J. Coulson Nick R. Glass Justin J. Cooper-White Bruno van Swinderen Frédéric A. Meunier
author_facet	Tong Wang Sally Martin Tam H. Nguyen Callista B. Harper Rachel S. Gormal Ramon Martínez-Mármol Shanker Karunanithi Elizabeth J. Coulson Nick R. Glass Justin J. Cooper-White Bruno van Swinderen Frédéric A. Meunier
author_sort	Tong Wang
title	Flux of signalling endosomes undergoing axonal retrograde transport is encoded by presynaptic activity and TrkB
title_short	Flux of signalling endosomes undergoing axonal retrograde transport is encoded by presynaptic activity and TrkB
title_full	Flux of signalling endosomes undergoing axonal retrograde transport is encoded by presynaptic activity and TrkB
title_fullStr	Flux of signalling endosomes undergoing axonal retrograde transport is encoded by presynaptic activity and TrkB
title_full_unstemmed	Flux of signalling endosomes undergoing axonal retrograde transport is encoded by presynaptic activity and TrkB
title_sort	flux of signalling endosomes undergoing axonal retrograde transport is encoded by presynaptic activity and trkb
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/be42e86f725a40bf81556fbeac83c206
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Flux of signalling endosomes undergoing axonal retrograde transport is encoded by presynaptic activity and TrkB

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