Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10

Here, the authors provide the structure of mature Coxsackie Virus A10 alone and in complex with its receptor KREMEN1, and of A-particles. This shows how the receptor spans the viral canyon and suggests that receptor binding triggers pocket factor release and conformational changes resulting in expan...

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Autores principales:	Yuguang Zhao, Daming Zhou, Tao Ni, Dimple Karia, Abhay Kotecha, Xiangxi Wang, Zihe Rao, E. Yvonne Jones, Elizabeth E. Fry, Jingshan Ren, David I. Stuart
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/be45168770654d1e8ea295697ed054b8
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spelling	oai:doaj.org-article:be45168770654d1e8ea295697ed054b82021-12-02T15:34:13ZHand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A1010.1038/s41467-019-13936-22041-1723https://doaj.org/article/be45168770654d1e8ea295697ed054b82020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13936-2https://doaj.org/toc/2041-1723Here, the authors provide the structure of mature Coxsackie Virus A10 alone and in complex with its receptor KREMEN1, and of A-particles. This shows how the receptor spans the viral canyon and suggests that receptor binding triggers pocket factor release and conformational changes resulting in expanded particles.Yuguang ZhaoDaming ZhouTao NiDimple KariaAbhay KotechaXiangxi WangZihe RaoE. Yvonne JonesElizabeth E. FryJingshan RenDavid I. StuartNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yuguang Zhao Daming Zhou Tao Ni Dimple Karia Abhay Kotecha Xiangxi Wang Zihe Rao E. Yvonne Jones Elizabeth E. Fry Jingshan Ren David I. Stuart Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10
description	Here, the authors provide the structure of mature Coxsackie Virus A10 alone and in complex with its receptor KREMEN1, and of A-particles. This shows how the receptor spans the viral canyon and suggests that receptor binding triggers pocket factor release and conformational changes resulting in expanded particles.
format	article
author	Yuguang Zhao Daming Zhou Tao Ni Dimple Karia Abhay Kotecha Xiangxi Wang Zihe Rao E. Yvonne Jones Elizabeth E. Fry Jingshan Ren David I. Stuart
author_facet	Yuguang Zhao Daming Zhou Tao Ni Dimple Karia Abhay Kotecha Xiangxi Wang Zihe Rao E. Yvonne Jones Elizabeth E. Fry Jingshan Ren David I. Stuart
author_sort	Yuguang Zhao
title	Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10
title_short	Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10
title_full	Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10
title_fullStr	Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10
title_full_unstemmed	Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10
title_sort	hand-foot-and-mouth disease virus receptor kremen1 binds the canyon of coxsackie virus a10
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/be45168770654d1e8ea295697ed054b8
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Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10

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