Tosylation of alcohols: an effective strategy for the functional group transformation of organic derivatives of polyoxometalates

Abstract Recently, the organic functionalization of polyoxometalates (POMs) has drawn increasing interest, and an easy and effective route to achieve organic derivatives is of great importance. Herein, the first reported synthesis of a tosyl ester derivative of the polyoxometalate (Bu4N)2[V6O13{(OCH...

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Autores principales:	Hongli Jia, Qi Li, Aruuhan Bayaguud, Shan She, Yichao Huang, Kun Chen, Yongge Wei
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/be4ee172b75447ee874ef889c196bfdc
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spelling	oai:doaj.org-article:be4ee172b75447ee874ef889c196bfdc2021-12-02T15:05:55ZTosylation of alcohols: an effective strategy for the functional group transformation of organic derivatives of polyoxometalates10.1038/s41598-017-12633-82045-2322https://doaj.org/article/be4ee172b75447ee874ef889c196bfdc2017-10-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-12633-8https://doaj.org/toc/2045-2322Abstract Recently, the organic functionalization of polyoxometalates (POMs) has drawn increasing interest, and an easy and effective route to achieve organic derivatives is of great importance. Herein, the first reported synthesis of a tosyl ester derivative of the polyoxometalate (Bu4N)2[V6O13{(OCH2)3CCH2SO3C7H4}2]·2.5CH3CN (compound 1) was performed by using DMAP as an activating reagent and triethylamine as an HCl scavenger. The tosyl ester was transformed into an azide or halide group by using sodium azide or sodium bromide, respectively, as the nucleophilic agent. Two derivatives of POMs, (Bu4N)2[V6O13{(OCH2)3CCH2N3}2]·4CH3CN (compound 2) and (Bu4N)2[V6O13{(OCH2)3CCH2Br}2] (compound 3), were easily obtained. All the compounds were structurally and compositionally characterized by single-crystal X-ray diffraction, elemental analysis, IR spectroscopy, NMR spectroscopy, ESI-MS, UV-Vis spectroscopy and TGA. This work provides a new route for the functional group transformation of organic derivatives of polyoxometalates.Hongli JiaQi LiAruuhan BayaguudShan SheYichao HuangKun ChenYongge WeiNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Hongli Jia Qi Li Aruuhan Bayaguud Shan She Yichao Huang Kun Chen Yongge Wei Tosylation of alcohols: an effective strategy for the functional group transformation of organic derivatives of polyoxometalates
description	Abstract Recently, the organic functionalization of polyoxometalates (POMs) has drawn increasing interest, and an easy and effective route to achieve organic derivatives is of great importance. Herein, the first reported synthesis of a tosyl ester derivative of the polyoxometalate (Bu4N)2[V6O13{(OCH2)3CCH2SO3C7H4}2]·2.5CH3CN (compound 1) was performed by using DMAP as an activating reagent and triethylamine as an HCl scavenger. The tosyl ester was transformed into an azide or halide group by using sodium azide or sodium bromide, respectively, as the nucleophilic agent. Two derivatives of POMs, (Bu4N)2[V6O13{(OCH2)3CCH2N3}2]·4CH3CN (compound 2) and (Bu4N)2[V6O13{(OCH2)3CCH2Br}2] (compound 3), were easily obtained. All the compounds were structurally and compositionally characterized by single-crystal X-ray diffraction, elemental analysis, IR spectroscopy, NMR spectroscopy, ESI-MS, UV-Vis spectroscopy and TGA. This work provides a new route for the functional group transformation of organic derivatives of polyoxometalates.
format	article
author	Hongli Jia Qi Li Aruuhan Bayaguud Shan She Yichao Huang Kun Chen Yongge Wei
author_facet	Hongli Jia Qi Li Aruuhan Bayaguud Shan She Yichao Huang Kun Chen Yongge Wei
author_sort	Hongli Jia
title	Tosylation of alcohols: an effective strategy for the functional group transformation of organic derivatives of polyoxometalates
title_short	Tosylation of alcohols: an effective strategy for the functional group transformation of organic derivatives of polyoxometalates
title_full	Tosylation of alcohols: an effective strategy for the functional group transformation of organic derivatives of polyoxometalates
title_fullStr	Tosylation of alcohols: an effective strategy for the functional group transformation of organic derivatives of polyoxometalates
title_full_unstemmed	Tosylation of alcohols: an effective strategy for the functional group transformation of organic derivatives of polyoxometalates
title_sort	tosylation of alcohols: an effective strategy for the functional group transformation of organic derivatives of polyoxometalates
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/be4ee172b75447ee874ef889c196bfdc
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Tosylation of alcohols: an effective strategy for the functional group transformation of organic derivatives of polyoxometalates

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