Glucose estimation in the salivary secretion of diabetes mellitus patients

Abikshyeet Panda,1 Ramesh Venkatapathy,2 Nirima Oza21Department of Oral Pathology, Kalinga Institute of Dental Sciences, Kalinga Institute of Industrial Technology University, Bhubaneswar, Odisha, 2Department of Oral Pathology and Microbiology, Mahatma Gandhi Post Graduate Institute of Dental Scienc...

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Autores principales:	Abikshyeet P, Ramesh V, Oza N
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2012
Materias:	Specialties of internal medicine RC581-951
Acceso en línea:	https://doaj.org/article/be513e19eed840fc95341567c7ce5669
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spelling	oai:doaj.org-article:be513e19eed840fc95341567c7ce56692021-12-02T03:15:28ZGlucose estimation in the salivary secretion of diabetes mellitus patients1178-7007https://doaj.org/article/be513e19eed840fc95341567c7ce56692012-07-01T00:00:00Zhttp://www.dovepress.com/glucose-estimation-in-the-salivary-secretion-of-diabetes-mellitus-pati-a10387https://doaj.org/toc/1178-7007Abikshyeet Panda,1 Ramesh Venkatapathy,2 Nirima Oza21Department of Oral Pathology, Kalinga Institute of Dental Sciences, Kalinga Institute of Industrial Technology University, Bhubaneswar, Odisha, 2Department of Oral Pathology and Microbiology, Mahatma Gandhi Post Graduate Institute of Dental Sciences, Puducherry, IndiaAim: Saliva is one of the most abundant secretions in the human body and its collection is easy and noninvasive. The aim of this study was to find a medium that can be used to diagnose and monitor diabetes. In this, saliva could play a major role. To substantiate the role of saliva as a diagnostic tool, we compared saliva samples with blood glucose and glycated hemoglobin (HbA1c) in healthy and diabetic subjects.Materials and methods: Included in the study were 106 patients, newly diagnosed with type 2 diabetes mellitus and 15 healthy control subjects. The patients and control subjects were asked to come to the clinic in the morning, after an 8-hour fast. At that time, 5 mL of venous blood was collected, 2 mL of which was collected in an ethylenediaminetetraacetic acid (EDTA)-containing blood collection tube and sent for HbA1c estimation. Unstimulated saliva was collected from both groups as well. The saliva and sera from the blood samples were subjected to glucose estimation.Results: The correlation coefficient between serum glucose and salivary glucose in the control group was calculated and the r value was found to be 0.5216, which was statistically significant (P &lt; 0.05). The correlation coefficient between serum glucose and salivary glucose in the patient group was also calculated and the r value was found to be 0.7686, which was highly significant (P &lt; 0.01). Finally, the correlation coefficient between HbA1c level and salivary glucose in the patient group was calculated and the r value was found to be 0.5662, which was also highly significant (P &lt; 0.01).Keywords: saliva, salivary glucose, serum glucose, insulin, hyperglycemiaAbikshyeet PRamesh VOza NDove Medical PressarticleSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol 2012, Iss default, Pp 149-154 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Specialties of internal medicine RC581-951
spellingShingle	Specialties of internal medicine RC581-951 Abikshyeet P Ramesh V Oza N Glucose estimation in the salivary secretion of diabetes mellitus patients
description	Abikshyeet Panda,1 Ramesh Venkatapathy,2 Nirima Oza21Department of Oral Pathology, Kalinga Institute of Dental Sciences, Kalinga Institute of Industrial Technology University, Bhubaneswar, Odisha, 2Department of Oral Pathology and Microbiology, Mahatma Gandhi Post Graduate Institute of Dental Sciences, Puducherry, IndiaAim: Saliva is one of the most abundant secretions in the human body and its collection is easy and noninvasive. The aim of this study was to find a medium that can be used to diagnose and monitor diabetes. In this, saliva could play a major role. To substantiate the role of saliva as a diagnostic tool, we compared saliva samples with blood glucose and glycated hemoglobin (HbA1c) in healthy and diabetic subjects.Materials and methods: Included in the study were 106 patients, newly diagnosed with type 2 diabetes mellitus and 15 healthy control subjects. The patients and control subjects were asked to come to the clinic in the morning, after an 8-hour fast. At that time, 5 mL of venous blood was collected, 2 mL of which was collected in an ethylenediaminetetraacetic acid (EDTA)-containing blood collection tube and sent for HbA1c estimation. Unstimulated saliva was collected from both groups as well. The saliva and sera from the blood samples were subjected to glucose estimation.Results: The correlation coefficient between serum glucose and salivary glucose in the control group was calculated and the r value was found to be 0.5216, which was statistically significant (P &lt; 0.05). The correlation coefficient between serum glucose and salivary glucose in the patient group was also calculated and the r value was found to be 0.7686, which was highly significant (P &lt; 0.01). Finally, the correlation coefficient between HbA1c level and salivary glucose in the patient group was calculated and the r value was found to be 0.5662, which was also highly significant (P &lt; 0.01).Keywords: saliva, salivary glucose, serum glucose, insulin, hyperglycemia
format	article
author	Abikshyeet P Ramesh V Oza N
author_facet	Abikshyeet P Ramesh V Oza N
author_sort	Abikshyeet P
title	Glucose estimation in the salivary secretion of diabetes mellitus patients
title_short	Glucose estimation in the salivary secretion of diabetes mellitus patients
title_full	Glucose estimation in the salivary secretion of diabetes mellitus patients
title_fullStr	Glucose estimation in the salivary secretion of diabetes mellitus patients
title_full_unstemmed	Glucose estimation in the salivary secretion of diabetes mellitus patients
title_sort	glucose estimation in the salivary secretion of diabetes mellitus patients
publisher	Dove Medical Press
publishDate	2012
url	https://doaj.org/article/be513e19eed840fc95341567c7ce5669
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Glucose estimation in the salivary secretion of diabetes mellitus patients

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