Distinct patterns of within-host virus populations between two subgroups of human respiratory syncytial virus

Respiratory syncytial virus (RSV) is a common infection in children and older adults but little is known about within-host viral population diversity. Here, the authors perform deep sequencing and find that RSV subgroup B exhibited more diversity than subgroup A, with implications for development of...

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Autores principales:	Gu-Lung Lin, Simon B. Drysdale, Matthew D. Snape, Daniel O’Connor, Anthony Brown, George MacIntyre-Cockett, Esther Mellado-Gomez, Mariateresa de Cesare, David Bonsall, M. Azim Ansari, Deniz Öner, Jeroen Aerssens, Christopher Butler, Louis Bont, Peter Openshaw, Federico Martinón-Torres, Harish Nair, Rory Bowden, RESCEU Investigators, Tanya Golubchik, Andrew J. Pollard
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/be54b219fed94f08b8ef4d94b0391eab
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spelling	oai:doaj.org-article:be54b219fed94f08b8ef4d94b0391eab2021-12-02T15:09:09ZDistinct patterns of within-host virus populations between two subgroups of human respiratory syncytial virus10.1038/s41467-021-25265-42041-1723https://doaj.org/article/be54b219fed94f08b8ef4d94b0391eab2021-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25265-4https://doaj.org/toc/2041-1723Respiratory syncytial virus (RSV) is a common infection in children and older adults but little is known about within-host viral population diversity. Here, the authors perform deep sequencing and find that RSV subgroup B exhibited more diversity than subgroup A, with implications for development of therapeutics and vaccines.Gu-Lung LinSimon B. DrysdaleMatthew D. SnapeDaniel O’ConnorAnthony BrownGeorge MacIntyre-CockettEsther Mellado-GomezMariateresa de CesareDavid BonsallM. Azim AnsariDeniz ÖnerJeroen AerssensChristopher ButlerLouis BontPeter OpenshawFederico Martinón-TorresHarish NairRory BowdenRESCEU InvestigatorsTanya GolubchikAndrew J. PollardNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Gu-Lung Lin Simon B. Drysdale Matthew D. Snape Daniel O’Connor Anthony Brown George MacIntyre-Cockett Esther Mellado-Gomez Mariateresa de Cesare David Bonsall M. Azim Ansari Deniz Öner Jeroen Aerssens Christopher Butler Louis Bont Peter Openshaw Federico Martinón-Torres Harish Nair Rory Bowden RESCEU Investigators Tanya Golubchik Andrew J. Pollard Distinct patterns of within-host virus populations between two subgroups of human respiratory syncytial virus
description	Respiratory syncytial virus (RSV) is a common infection in children and older adults but little is known about within-host viral population diversity. Here, the authors perform deep sequencing and find that RSV subgroup B exhibited more diversity than subgroup A, with implications for development of therapeutics and vaccines.
format	article
author	Gu-Lung Lin Simon B. Drysdale Matthew D. Snape Daniel O’Connor Anthony Brown George MacIntyre-Cockett Esther Mellado-Gomez Mariateresa de Cesare David Bonsall M. Azim Ansari Deniz Öner Jeroen Aerssens Christopher Butler Louis Bont Peter Openshaw Federico Martinón-Torres Harish Nair Rory Bowden RESCEU Investigators Tanya Golubchik Andrew J. Pollard
author_facet	Gu-Lung Lin Simon B. Drysdale Matthew D. Snape Daniel O’Connor Anthony Brown George MacIntyre-Cockett Esther Mellado-Gomez Mariateresa de Cesare David Bonsall M. Azim Ansari Deniz Öner Jeroen Aerssens Christopher Butler Louis Bont Peter Openshaw Federico Martinón-Torres Harish Nair Rory Bowden RESCEU Investigators Tanya Golubchik Andrew J. Pollard
author_sort	Gu-Lung Lin
title	Distinct patterns of within-host virus populations between two subgroups of human respiratory syncytial virus
title_short	Distinct patterns of within-host virus populations between two subgroups of human respiratory syncytial virus
title_full	Distinct patterns of within-host virus populations between two subgroups of human respiratory syncytial virus
title_fullStr	Distinct patterns of within-host virus populations between two subgroups of human respiratory syncytial virus
title_full_unstemmed	Distinct patterns of within-host virus populations between two subgroups of human respiratory syncytial virus
title_sort	distinct patterns of within-host virus populations between two subgroups of human respiratory syncytial virus
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/be54b219fed94f08b8ef4d94b0391eab
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Distinct patterns of within-host virus populations between two subgroups of human respiratory syncytial virus

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