Environmental eustress modulates β-ARs/CCL2 axis to induce anti-tumor immunity and sensitize immunotherapy against liver cancer in mice

The impact of positive environment stimulations (eustress) on cancer biology remains poorly understood. Here the authors show that exposure to an environment enrichment stimulates anti-tumor immunity and reduces tumor growth in preclinical models of liver cancer.

Guardado en:

Detalles Bibliográficos
Autores principales:	Chaobao Liu, Yang Yang, Cheng Chen, Ling Li, Jingquan Li, Xiaonan Wang, Qiao Chu, Lin Qiu, Qian Ba, Xiaoguang Li, Hui Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/be5a062266a54b60a3d9d8b31385a8f8
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:be5a062266a54b60a3d9d8b31385a8f8
record_format	dspace
spelling	oai:doaj.org-article:be5a062266a54b60a3d9d8b31385a8f82021-12-02T18:51:37ZEnvironmental eustress modulates β-ARs/CCL2 axis to induce anti-tumor immunity and sensitize immunotherapy against liver cancer in mice10.1038/s41467-021-25967-92041-1723https://doaj.org/article/be5a062266a54b60a3d9d8b31385a8f82021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25967-9https://doaj.org/toc/2041-1723The impact of positive environment stimulations (eustress) on cancer biology remains poorly understood. Here the authors show that exposure to an environment enrichment stimulates anti-tumor immunity and reduces tumor growth in preclinical models of liver cancer.Chaobao LiuYang YangCheng ChenLing LiJingquan LiXiaonan WangQiao ChuLin QiuQian BaXiaoguang LiHui WangNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chaobao Liu Yang Yang Cheng Chen Ling Li Jingquan Li Xiaonan Wang Qiao Chu Lin Qiu Qian Ba Xiaoguang Li Hui Wang Environmental eustress modulates β-ARs/CCL2 axis to induce anti-tumor immunity and sensitize immunotherapy against liver cancer in mice
description	The impact of positive environment stimulations (eustress) on cancer biology remains poorly understood. Here the authors show that exposure to an environment enrichment stimulates anti-tumor immunity and reduces tumor growth in preclinical models of liver cancer.
format	article
author	Chaobao Liu Yang Yang Cheng Chen Ling Li Jingquan Li Xiaonan Wang Qiao Chu Lin Qiu Qian Ba Xiaoguang Li Hui Wang
author_facet	Chaobao Liu Yang Yang Cheng Chen Ling Li Jingquan Li Xiaonan Wang Qiao Chu Lin Qiu Qian Ba Xiaoguang Li Hui Wang
author_sort	Chaobao Liu
title	Environmental eustress modulates β-ARs/CCL2 axis to induce anti-tumor immunity and sensitize immunotherapy against liver cancer in mice
title_short	Environmental eustress modulates β-ARs/CCL2 axis to induce anti-tumor immunity and sensitize immunotherapy against liver cancer in mice
title_full	Environmental eustress modulates β-ARs/CCL2 axis to induce anti-tumor immunity and sensitize immunotherapy against liver cancer in mice
title_fullStr	Environmental eustress modulates β-ARs/CCL2 axis to induce anti-tumor immunity and sensitize immunotherapy against liver cancer in mice
title_full_unstemmed	Environmental eustress modulates β-ARs/CCL2 axis to induce anti-tumor immunity and sensitize immunotherapy against liver cancer in mice
title_sort	environmental eustress modulates β-ars/ccl2 axis to induce anti-tumor immunity and sensitize immunotherapy against liver cancer in mice
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/be5a062266a54b60a3d9d8b31385a8f8
work_keys_str_mv	AT chaobaoliu environmentaleustressmodulatesbarsccl2axistoinduceantitumorimmunityandsensitizeimmunotherapyagainstlivercancerinmice AT yangyang environmentaleustressmodulatesbarsccl2axistoinduceantitumorimmunityandsensitizeimmunotherapyagainstlivercancerinmice AT chengchen environmentaleustressmodulatesbarsccl2axistoinduceantitumorimmunityandsensitizeimmunotherapyagainstlivercancerinmice AT lingli environmentaleustressmodulatesbarsccl2axistoinduceantitumorimmunityandsensitizeimmunotherapyagainstlivercancerinmice AT jingquanli environmentaleustressmodulatesbarsccl2axistoinduceantitumorimmunityandsensitizeimmunotherapyagainstlivercancerinmice AT xiaonanwang environmentaleustressmodulatesbarsccl2axistoinduceantitumorimmunityandsensitizeimmunotherapyagainstlivercancerinmice AT qiaochu environmentaleustressmodulatesbarsccl2axistoinduceantitumorimmunityandsensitizeimmunotherapyagainstlivercancerinmice AT linqiu environmentaleustressmodulatesbarsccl2axistoinduceantitumorimmunityandsensitizeimmunotherapyagainstlivercancerinmice AT qianba environmentaleustressmodulatesbarsccl2axistoinduceantitumorimmunityandsensitizeimmunotherapyagainstlivercancerinmice AT xiaoguangli environmentaleustressmodulatesbarsccl2axistoinduceantitumorimmunityandsensitizeimmunotherapyagainstlivercancerinmice AT huiwang environmentaleustressmodulatesbarsccl2axistoinduceantitumorimmunityandsensitizeimmunotherapyagainstlivercancerinmice
_version_	1718377408962232320

Environmental eustress modulates β-ARs/CCL2 axis to induce anti-tumor immunity and sensitize immunotherapy against liver cancer in mice

Ejemplares similares