Experimental Study of the Laser-Induced Oxyhemoglobin Photodissociation in Cutaneous Blood Vessels

A new optical method for reduction of local tissue hypoxia is proposed. It is shown that this method of phototherapy allows the control of a local oxygen concentration in tissue. Different aspects of biomedical application of this phenomenon are discussed. The results of in vivo experimental investi...

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Autores principales: Gisbrecht Alexander, Mamilov S.
Formato: article
Lenguaje:EN
Publicado: Sciendo 2015
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Acceso en línea:https://doaj.org/article/be6c22cae5a64ce1a45a43649939ad52
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spelling oai:doaj.org-article:be6c22cae5a64ce1a45a43649939ad522021-12-02T17:31:48ZExperimental Study of the Laser-Induced Oxyhemoglobin Photodissociation in Cutaneous Blood Vessels0324-175010.1515/amb-2015-0017https://doaj.org/article/be6c22cae5a64ce1a45a43649939ad522015-11-01T00:00:00Zhttps://doi.org/10.1515/amb-2015-0017https://doaj.org/toc/0324-1750A new optical method for reduction of local tissue hypoxia is proposed. It is shown that this method of phototherapy allows the control of a local oxygen concentration in tissue. Different aspects of biomedical application of this phenomenon are discussed. The results of in vivo experimental investigation of the laser-induced photodissociation of oxyhemoglobin in cutaneous blood vessels and its role in tissue oxygenation are presented. The rates of oxygen saturation SpO2 in blood and their dependence on the wavelength of the transcutaneous laser irradiation have been experimentally measured.Gisbrecht AlexanderMamilov S.Sciendoarticleoxyhemoglobintissue oxygenationhypoxiaphototherapyphotodissociationMedicineRENActa Medica Bulgarica, Vol 42, Iss 2, Pp 42-48 (2015)
institution DOAJ
collection DOAJ
language EN
topic oxyhemoglobin
tissue oxygenation
hypoxia
phototherapy
photodissociation
Medicine
R
spellingShingle oxyhemoglobin
tissue oxygenation
hypoxia
phototherapy
photodissociation
Medicine
R
Gisbrecht Alexander
Mamilov S.
Experimental Study of the Laser-Induced Oxyhemoglobin Photodissociation in Cutaneous Blood Vessels
description A new optical method for reduction of local tissue hypoxia is proposed. It is shown that this method of phototherapy allows the control of a local oxygen concentration in tissue. Different aspects of biomedical application of this phenomenon are discussed. The results of in vivo experimental investigation of the laser-induced photodissociation of oxyhemoglobin in cutaneous blood vessels and its role in tissue oxygenation are presented. The rates of oxygen saturation SpO2 in blood and their dependence on the wavelength of the transcutaneous laser irradiation have been experimentally measured.
format article
author Gisbrecht Alexander
Mamilov S.
author_facet Gisbrecht Alexander
Mamilov S.
author_sort Gisbrecht Alexander
title Experimental Study of the Laser-Induced Oxyhemoglobin Photodissociation in Cutaneous Blood Vessels
title_short Experimental Study of the Laser-Induced Oxyhemoglobin Photodissociation in Cutaneous Blood Vessels
title_full Experimental Study of the Laser-Induced Oxyhemoglobin Photodissociation in Cutaneous Blood Vessels
title_fullStr Experimental Study of the Laser-Induced Oxyhemoglobin Photodissociation in Cutaneous Blood Vessels
title_full_unstemmed Experimental Study of the Laser-Induced Oxyhemoglobin Photodissociation in Cutaneous Blood Vessels
title_sort experimental study of the laser-induced oxyhemoglobin photodissociation in cutaneous blood vessels
publisher Sciendo
publishDate 2015
url https://doaj.org/article/be6c22cae5a64ce1a45a43649939ad52
work_keys_str_mv AT gisbrechtalexander experimentalstudyofthelaserinducedoxyhemoglobinphotodissociationincutaneousbloodvessels
AT mamilovs experimentalstudyofthelaserinducedoxyhemoglobinphotodissociationincutaneousbloodvessels
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