Genome scale patterns of supercoiling in a bacterial chromosome

Bacterial DNA primarily exists in a negatively supercoiled or under-wound state. Here, by mapping the supercoiling state, the authors show that there is a gradient of supercoiling across the bacterial chromosome with the terminus being more negatively supercoiled than the origin.

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Autores principales:	Avantika Lal, Amlanjyoti Dhar, Andrei Trostel, Fedor Kouzine, Aswin S. N. Seshasayee, Sankar Adhya
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/be7611785c574ff2bbac48aeae9ad064
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id	oai:doaj.org-article:be7611785c574ff2bbac48aeae9ad064
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spelling	oai:doaj.org-article:be7611785c574ff2bbac48aeae9ad0642021-12-02T16:56:45ZGenome scale patterns of supercoiling in a bacterial chromosome10.1038/ncomms110552041-1723https://doaj.org/article/be7611785c574ff2bbac48aeae9ad0642016-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms11055https://doaj.org/toc/2041-1723Bacterial DNA primarily exists in a negatively supercoiled or under-wound state. Here, by mapping the supercoiling state, the authors show that there is a gradient of supercoiling across the bacterial chromosome with the terminus being more negatively supercoiled than the origin.Avantika LalAmlanjyoti DharAndrei TrostelFedor KouzineAswin S. N. SeshasayeeSankar AdhyaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Avantika Lal Amlanjyoti Dhar Andrei Trostel Fedor Kouzine Aswin S. N. Seshasayee Sankar Adhya Genome scale patterns of supercoiling in a bacterial chromosome
description	Bacterial DNA primarily exists in a negatively supercoiled or under-wound state. Here, by mapping the supercoiling state, the authors show that there is a gradient of supercoiling across the bacterial chromosome with the terminus being more negatively supercoiled than the origin.
format	article
author	Avantika Lal Amlanjyoti Dhar Andrei Trostel Fedor Kouzine Aswin S. N. Seshasayee Sankar Adhya
author_facet	Avantika Lal Amlanjyoti Dhar Andrei Trostel Fedor Kouzine Aswin S. N. Seshasayee Sankar Adhya
author_sort	Avantika Lal
title	Genome scale patterns of supercoiling in a bacterial chromosome
title_short	Genome scale patterns of supercoiling in a bacterial chromosome
title_full	Genome scale patterns of supercoiling in a bacterial chromosome
title_fullStr	Genome scale patterns of supercoiling in a bacterial chromosome
title_full_unstemmed	Genome scale patterns of supercoiling in a bacterial chromosome
title_sort	genome scale patterns of supercoiling in a bacterial chromosome
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/be7611785c574ff2bbac48aeae9ad064
work_keys_str_mv	AT avantikalal genomescalepatternsofsupercoilinginabacterialchromosome AT amlanjyotidhar genomescalepatternsofsupercoilinginabacterialchromosome AT andreitrostel genomescalepatternsofsupercoilinginabacterialchromosome AT fedorkouzine genomescalepatternsofsupercoilinginabacterialchromosome AT aswinsnseshasayee genomescalepatternsofsupercoilinginabacterialchromosome AT sankaradhya genomescalepatternsofsupercoilinginabacterialchromosome
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Genome scale patterns of supercoiling in a bacterial chromosome

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