Resurgent Na+ currents promote ultrafast spiking in projection neurons that drive fine motor control

The zebra finch robust nucleus of the arcopallium (RA) directs singing by providing descending projections to brainstem motor neurons. The authors show that electrophysiological characteristics of RA neurons rely on resurgent Na+ currents that emerge early during song development only in males.

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Autores principales: Benjamin M. Zemel, Alexander A. Nevue, Andre Dagostin, Peter V. Lovell, Claudio V. Mello, Henrique von Gersdorff
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/be7c6dc576af491bb613826e88f66a66
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spelling oai:doaj.org-article:be7c6dc576af491bb613826e88f66a662021-11-21T12:38:53ZResurgent Na+ currents promote ultrafast spiking in projection neurons that drive fine motor control10.1038/s41467-021-26521-32041-1723https://doaj.org/article/be7c6dc576af491bb613826e88f66a662021-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-26521-3https://doaj.org/toc/2041-1723The zebra finch robust nucleus of the arcopallium (RA) directs singing by providing descending projections to brainstem motor neurons. The authors show that electrophysiological characteristics of RA neurons rely on resurgent Na+ currents that emerge early during song development only in males.Benjamin M. ZemelAlexander A. NevueAndre DagostinPeter V. LovellClaudio V. MelloHenrique von GersdorffNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-23 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Benjamin M. Zemel
Alexander A. Nevue
Andre Dagostin
Peter V. Lovell
Claudio V. Mello
Henrique von Gersdorff
Resurgent Na+ currents promote ultrafast spiking in projection neurons that drive fine motor control
description The zebra finch robust nucleus of the arcopallium (RA) directs singing by providing descending projections to brainstem motor neurons. The authors show that electrophysiological characteristics of RA neurons rely on resurgent Na+ currents that emerge early during song development only in males.
format article
author Benjamin M. Zemel
Alexander A. Nevue
Andre Dagostin
Peter V. Lovell
Claudio V. Mello
Henrique von Gersdorff
author_facet Benjamin M. Zemel
Alexander A. Nevue
Andre Dagostin
Peter V. Lovell
Claudio V. Mello
Henrique von Gersdorff
author_sort Benjamin M. Zemel
title Resurgent Na+ currents promote ultrafast spiking in projection neurons that drive fine motor control
title_short Resurgent Na+ currents promote ultrafast spiking in projection neurons that drive fine motor control
title_full Resurgent Na+ currents promote ultrafast spiking in projection neurons that drive fine motor control
title_fullStr Resurgent Na+ currents promote ultrafast spiking in projection neurons that drive fine motor control
title_full_unstemmed Resurgent Na+ currents promote ultrafast spiking in projection neurons that drive fine motor control
title_sort resurgent na+ currents promote ultrafast spiking in projection neurons that drive fine motor control
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/be7c6dc576af491bb613826e88f66a66
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