SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival

T-acute lymphoblastic leukemia is an aggressive cancer. Here the authors provide insights into the functional role of SHQ1, an H/ACA snoRNP assembly factor involved in snRNA pseudouridylation, in T-lymphoblastic leukemia cell survival through regulating the maturation of MYC mRNA.

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Autores principales:	Hexiu Su, Juncheng Hu, Liang Huang, Yang Yang, Morgan Thenoz, Anna Kuchmiy, Yufeng Hu, Peng Li, Hui Feng, Yu Zhou, Tom Taghon, Pieter Van Vlierberghe, Guoliang Qing, Zhichao Chen, Hudan Liu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/be84c2167969446dbc4de6875a3ebd48
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:be84c2167969446dbc4de6875a3ebd482021-12-02T16:56:44ZSHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival10.1038/s41467-018-06523-42041-1723https://doaj.org/article/be84c2167969446dbc4de6875a3ebd482018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06523-4https://doaj.org/toc/2041-1723T-acute lymphoblastic leukemia is an aggressive cancer. Here the authors provide insights into the functional role of SHQ1, an H/ACA snoRNP assembly factor involved in snRNA pseudouridylation, in T-lymphoblastic leukemia cell survival through regulating the maturation of MYC mRNA.Hexiu SuJuncheng HuLiang HuangYang YangMorgan ThenozAnna KuchmiyYufeng HuPeng LiHui FengYu ZhouTom TaghonPieter Van VlierbergheGuoliang QingZhichao ChenHudan LiuNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Hexiu Su Juncheng Hu Liang Huang Yang Yang Morgan Thenoz Anna Kuchmiy Yufeng Hu Peng Li Hui Feng Yu Zhou Tom Taghon Pieter Van Vlierberghe Guoliang Qing Zhichao Chen Hudan Liu SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival
description	T-acute lymphoblastic leukemia is an aggressive cancer. Here the authors provide insights into the functional role of SHQ1, an H/ACA snoRNP assembly factor involved in snRNA pseudouridylation, in T-lymphoblastic leukemia cell survival through regulating the maturation of MYC mRNA.
format	article
author	Hexiu Su Juncheng Hu Liang Huang Yang Yang Morgan Thenoz Anna Kuchmiy Yufeng Hu Peng Li Hui Feng Yu Zhou Tom Taghon Pieter Van Vlierberghe Guoliang Qing Zhichao Chen Hudan Liu
author_facet	Hexiu Su Juncheng Hu Liang Huang Yang Yang Morgan Thenoz Anna Kuchmiy Yufeng Hu Peng Li Hui Feng Yu Zhou Tom Taghon Pieter Van Vlierberghe Guoliang Qing Zhichao Chen Hudan Liu
author_sort	Hexiu Su
title	SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival
title_short	SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival
title_full	SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival
title_fullStr	SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival
title_full_unstemmed	SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival
title_sort	shq1 regulation of rna splicing is required for t-lymphoblastic leukemia cell survival
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/be84c2167969446dbc4de6875a3ebd48
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SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival

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