Viral Inactivation Impacts Microbiome Estimates in a Tissue-Specific Manner

Understanding how viral infections impact and are modulated by the microbiome is an important problem in basic research but is also of high clinical relevance under the current pandemic. To facilitate the study of interactions between microbial communities and pathogenic viruses under safe conditio...

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Autores principales: Alba Boix-Amorós, Enrica Piras, Kevin Bu, David Wallach, Matthew Stapylton, Ana Fernández-Sesma, Dolores Malaspina, Jose C. Clemente
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/be88ce4b05164f42b03f4381e1a7186b
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Sumario:Understanding how viral infections impact and are modulated by the microbiome is an important problem in basic research but is also of high clinical relevance under the current pandemic. To facilitate the study of interactions between microbial communities and pathogenic viruses under safe conditions, the infectious agent is generally inactivated prior to processing samples.