Identification of a peptide recognizing cerebrovascular changes in mouse models of Alzheimer’s disease

Cerebrovascular changes and astrogliosis occur in Alzheimer’s disease (AD). Using an in vivo phage display technique, the authors identified a peptide that upon systematic administration, can home to brain endothelial cells and astrocytes in mouse models of AD at the early stages of the disease.

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Autores principales:	Aman P. Mann, Pablo Scodeller, Sazid Hussain, Gary B. Braun, Tarmo Mölder, Kadri Toome, Rajesh Ambasudhan, Tambet Teesalu, Stuart A. Lipton, Erkki Ruoslahti
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/be95d3c6783044f889e270600ff9b0e4
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spelling	oai:doaj.org-article:be95d3c6783044f889e270600ff9b0e42021-12-02T17:05:59ZIdentification of a peptide recognizing cerebrovascular changes in mouse models of Alzheimer’s disease10.1038/s41467-017-01096-02041-1723https://doaj.org/article/be95d3c6783044f889e270600ff9b0e42017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01096-0https://doaj.org/toc/2041-1723Cerebrovascular changes and astrogliosis occur in Alzheimer’s disease (AD). Using an in vivo phage display technique, the authors identified a peptide that upon systematic administration, can home to brain endothelial cells and astrocytes in mouse models of AD at the early stages of the disease.Aman P. MannPablo ScodellerSazid HussainGary B. BraunTarmo MölderKadri ToomeRajesh AmbasudhanTambet TeesaluStuart A. LiptonErkki RuoslahtiNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Aman P. Mann Pablo Scodeller Sazid Hussain Gary B. Braun Tarmo Mölder Kadri Toome Rajesh Ambasudhan Tambet Teesalu Stuart A. Lipton Erkki Ruoslahti Identification of a peptide recognizing cerebrovascular changes in mouse models of Alzheimer’s disease
description	Cerebrovascular changes and astrogliosis occur in Alzheimer’s disease (AD). Using an in vivo phage display technique, the authors identified a peptide that upon systematic administration, can home to brain endothelial cells and astrocytes in mouse models of AD at the early stages of the disease.
format	article
author	Aman P. Mann Pablo Scodeller Sazid Hussain Gary B. Braun Tarmo Mölder Kadri Toome Rajesh Ambasudhan Tambet Teesalu Stuart A. Lipton Erkki Ruoslahti
author_facet	Aman P. Mann Pablo Scodeller Sazid Hussain Gary B. Braun Tarmo Mölder Kadri Toome Rajesh Ambasudhan Tambet Teesalu Stuart A. Lipton Erkki Ruoslahti
author_sort	Aman P. Mann
title	Identification of a peptide recognizing cerebrovascular changes in mouse models of Alzheimer’s disease
title_short	Identification of a peptide recognizing cerebrovascular changes in mouse models of Alzheimer’s disease
title_full	Identification of a peptide recognizing cerebrovascular changes in mouse models of Alzheimer’s disease
title_fullStr	Identification of a peptide recognizing cerebrovascular changes in mouse models of Alzheimer’s disease
title_full_unstemmed	Identification of a peptide recognizing cerebrovascular changes in mouse models of Alzheimer’s disease
title_sort	identification of a peptide recognizing cerebrovascular changes in mouse models of alzheimer’s disease
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/be95d3c6783044f889e270600ff9b0e4
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Identification of a peptide recognizing cerebrovascular changes in mouse models of Alzheimer’s disease

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