Molecular rheotaxis directs DNA migration and concentration against a pressure-driven flow

Implementing a nucleic acid preconcentration method can improve the sensitivity of microfluidic analysis systems. Here Friedrich et al. concentrate DNA by many orders of magnitude using pressure-driven flow, which could lead to a simple and practical microanalysis platform.

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Detalles Bibliográficos
Autores principales: Sarah M. Friedrich, Jeffrey M. Burke, Kelvin J. Liu, Cornelius F. Ivory, Tza-Huei Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/be96a85d1e7e4c87a20d2f0eaaddda44
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Sumario:Implementing a nucleic acid preconcentration method can improve the sensitivity of microfluidic analysis systems. Here Friedrich et al. concentrate DNA by many orders of magnitude using pressure-driven flow, which could lead to a simple and practical microanalysis platform.