Molecular rheotaxis directs DNA migration and concentration against a pressure-driven flow
Implementing a nucleic acid preconcentration method can improve the sensitivity of microfluidic analysis systems. Here Friedrich et al. concentrate DNA by many orders of magnitude using pressure-driven flow, which could lead to a simple and practical microanalysis platform.
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Nature Portfolio
2017
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oai:doaj.org-article:be96a85d1e7e4c87a20d2f0eaaddda442021-12-02T14:42:08ZMolecular rheotaxis directs DNA migration and concentration against a pressure-driven flow10.1038/s41467-017-01214-y2041-1723https://doaj.org/article/be96a85d1e7e4c87a20d2f0eaaddda442017-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01214-yhttps://doaj.org/toc/2041-1723Implementing a nucleic acid preconcentration method can improve the sensitivity of microfluidic analysis systems. Here Friedrich et al. concentrate DNA by many orders of magnitude using pressure-driven flow, which could lead to a simple and practical microanalysis platform.Sarah M. FriedrichJeffrey M. BurkeKelvin J. LiuCornelius F. IvoryTza-Huei WangNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017) |
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Science Q Sarah M. Friedrich Jeffrey M. Burke Kelvin J. Liu Cornelius F. Ivory Tza-Huei Wang Molecular rheotaxis directs DNA migration and concentration against a pressure-driven flow |
description |
Implementing a nucleic acid preconcentration method can improve the sensitivity of microfluidic analysis systems. Here Friedrich et al. concentrate DNA by many orders of magnitude using pressure-driven flow, which could lead to a simple and practical microanalysis platform. |
format |
article |
author |
Sarah M. Friedrich Jeffrey M. Burke Kelvin J. Liu Cornelius F. Ivory Tza-Huei Wang |
author_facet |
Sarah M. Friedrich Jeffrey M. Burke Kelvin J. Liu Cornelius F. Ivory Tza-Huei Wang |
author_sort |
Sarah M. Friedrich |
title |
Molecular rheotaxis directs DNA migration and concentration against a pressure-driven flow |
title_short |
Molecular rheotaxis directs DNA migration and concentration against a pressure-driven flow |
title_full |
Molecular rheotaxis directs DNA migration and concentration against a pressure-driven flow |
title_fullStr |
Molecular rheotaxis directs DNA migration and concentration against a pressure-driven flow |
title_full_unstemmed |
Molecular rheotaxis directs DNA migration and concentration against a pressure-driven flow |
title_sort |
molecular rheotaxis directs dna migration and concentration against a pressure-driven flow |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/be96a85d1e7e4c87a20d2f0eaaddda44 |
work_keys_str_mv |
AT sarahmfriedrich molecularrheotaxisdirectsdnamigrationandconcentrationagainstapressuredrivenflow AT jeffreymburke molecularrheotaxisdirectsdnamigrationandconcentrationagainstapressuredrivenflow AT kelvinjliu molecularrheotaxisdirectsdnamigrationandconcentrationagainstapressuredrivenflow AT corneliusfivory molecularrheotaxisdirectsdnamigrationandconcentrationagainstapressuredrivenflow AT tzahueiwang molecularrheotaxisdirectsdnamigrationandconcentrationagainstapressuredrivenflow |
_version_ |
1718389776261840896 |