REPRESENTATION OF DIFFERENT LYMPHOCYTES' POPULATIONS IN PERIPHERAL BLOOD OF PATIENTS WITH UTERINE MYOMA

Abstract. Uterine myoma is one of the most widespread gynecological pathology among reproductive women older than 30 years. It is known, that often progress of this pathology is associated with genetic and endocrinologic factors. The immune system is not evident still. The aim of this study was to a...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ye. E. Zueva, N. V. Kulagina, L. S. Komarova, A. V. Kurtova, I. V. Molchanova, E. F. Alekseeva, Areg A. Totolian
Formato:	article
Lenguaje:	RU
Publicado:	SPb RAACI 2014
Materias:	simple form of the uterine myoma proliferating form of the uterine myoma immune status flow cytometry Immunologic diseases. Allergy RC581-607
Acceso en línea:	https://doaj.org/article/be9b0d8146a841b98f0975d5795cde48
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:be9b0d8146a841b98f0975d5795cde48
record_format	dspace
spelling	oai:doaj.org-article:be9b0d8146a841b98f0975d5795cde482021-11-18T08:03:43ZREPRESENTATION OF DIFFERENT LYMPHOCYTES' POPULATIONS IN PERIPHERAL BLOOD OF PATIENTS WITH UTERINE MYOMA1563-06252313-741X10.15789/1563-0625-2005-5-6-535-542https://doaj.org/article/be9b0d8146a841b98f0975d5795cde482014-07-01T00:00:00Zhttps://www.mimmun.ru/mimmun/article/view/620https://doaj.org/toc/1563-0625https://doaj.org/toc/2313-741XAbstract. Uterine myoma is one of the most widespread gynecological pathology among reproductive women older than 30 years. It is known, that often progress of this pathology is associated with genetic and endocrinologic factors. The immune system is not evident still. The aim of this study was to analyze the state of patient's immune system using flow cytometry assessment of different subpopulations of lymphocytes in peripheral blood. We have examined 46 patients with simple and proliferating forms of the myoma, with different variants of clinical symptoms. Absolute and relative content of different subpopulations of lymphocytes was not differed from normal population's standard. Significant differences of B-lymphocytes and natural killers content were observed between groups with simple and proliferating forms of disease. It was shown that metrorrhagia is associated with high level of T-lymphocytes and T-killers. It was noted that decreasing of B-lymphocytes content took place in cases with large number of uterine nodes. Obtained data are not sufficient for complete understanding of the role of immune system in pathogenesis of this disease, but they confirm that using of immunomodulating therapy is expedient for complex treatment of uterine myoma.Ye. E. ZuevaN. V. KulaginaL. S. KomarovaA. V. KurtovaI. V. MolchanovaE. F. AlekseevaAreg A. TotolianSPb RAACIarticlesimple form of the uterine myomaproliferating form of the uterine myomaimmune statusflow cytometryImmunologic diseases. AllergyRC581-607RUMedicinskaâ Immunologiâ, Vol 7, Iss 5-6, Pp 535-542 (2014)
institution	DOAJ
collection	DOAJ
language	RU
topic	simple form of the uterine myoma proliferating form of the uterine myoma immune status flow cytometry Immunologic diseases. Allergy RC581-607
spellingShingle	simple form of the uterine myoma proliferating form of the uterine myoma immune status flow cytometry Immunologic diseases. Allergy RC581-607 Ye. E. Zueva N. V. Kulagina L. S. Komarova A. V. Kurtova I. V. Molchanova E. F. Alekseeva Areg A. Totolian REPRESENTATION OF DIFFERENT LYMPHOCYTES' POPULATIONS IN PERIPHERAL BLOOD OF PATIENTS WITH UTERINE MYOMA
description	Abstract. Uterine myoma is one of the most widespread gynecological pathology among reproductive women older than 30 years. It is known, that often progress of this pathology is associated with genetic and endocrinologic factors. The immune system is not evident still. The aim of this study was to analyze the state of patient's immune system using flow cytometry assessment of different subpopulations of lymphocytes in peripheral blood. We have examined 46 patients with simple and proliferating forms of the myoma, with different variants of clinical symptoms. Absolute and relative content of different subpopulations of lymphocytes was not differed from normal population's standard. Significant differences of B-lymphocytes and natural killers content were observed between groups with simple and proliferating forms of disease. It was shown that metrorrhagia is associated with high level of T-lymphocytes and T-killers. It was noted that decreasing of B-lymphocytes content took place in cases with large number of uterine nodes. Obtained data are not sufficient for complete understanding of the role of immune system in pathogenesis of this disease, but they confirm that using of immunomodulating therapy is expedient for complex treatment of uterine myoma.
format	article
author	Ye. E. Zueva N. V. Kulagina L. S. Komarova A. V. Kurtova I. V. Molchanova E. F. Alekseeva Areg A. Totolian
author_facet	Ye. E. Zueva N. V. Kulagina L. S. Komarova A. V. Kurtova I. V. Molchanova E. F. Alekseeva Areg A. Totolian
author_sort	Ye. E. Zueva
title	REPRESENTATION OF DIFFERENT LYMPHOCYTES' POPULATIONS IN PERIPHERAL BLOOD OF PATIENTS WITH UTERINE MYOMA
title_short	REPRESENTATION OF DIFFERENT LYMPHOCYTES' POPULATIONS IN PERIPHERAL BLOOD OF PATIENTS WITH UTERINE MYOMA
title_full	REPRESENTATION OF DIFFERENT LYMPHOCYTES' POPULATIONS IN PERIPHERAL BLOOD OF PATIENTS WITH UTERINE MYOMA
title_fullStr	REPRESENTATION OF DIFFERENT LYMPHOCYTES' POPULATIONS IN PERIPHERAL BLOOD OF PATIENTS WITH UTERINE MYOMA
title_full_unstemmed	REPRESENTATION OF DIFFERENT LYMPHOCYTES' POPULATIONS IN PERIPHERAL BLOOD OF PATIENTS WITH UTERINE MYOMA
title_sort	representation of different lymphocytes' populations in peripheral blood of patients with uterine myoma
publisher	SPb RAACI
publishDate	2014
url	https://doaj.org/article/be9b0d8146a841b98f0975d5795cde48
work_keys_str_mv	AT yeezueva representationofdifferentlymphocytespopulationsinperipheralbloodofpatientswithuterinemyoma AT nvkulagina representationofdifferentlymphocytespopulationsinperipheralbloodofpatientswithuterinemyoma AT lskomarova representationofdifferentlymphocytespopulationsinperipheralbloodofpatientswithuterinemyoma AT avkurtova representationofdifferentlymphocytespopulationsinperipheralbloodofpatientswithuterinemyoma AT ivmolchanova representationofdifferentlymphocytespopulationsinperipheralbloodofpatientswithuterinemyoma AT efalekseeva representationofdifferentlymphocytespopulationsinperipheralbloodofpatientswithuterinemyoma AT aregatotolian representationofdifferentlymphocytespopulationsinperipheralbloodofpatientswithuterinemyoma
_version_	1718422444410142720

REPRESENTATION OF DIFFERENT LYMPHOCYTES' POPULATIONS IN PERIPHERAL BLOOD OF PATIENTS WITH UTERINE MYOMA

Ejemplares similares