Tp63-expressing adult epithelial stem cells cross lineages boundaries revealing latent hairy skin competence

Adult stem cells are thought to be fate restricted to lineages distinct to their tissue of origin. Here, the authors demonstrate that Tp63 expressing epithelial stem cells from several disparate tissues can respond to skin morphogenetic signals and contribute to hair follicles, sebaceous glands and/...

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Autores principales:	Stéphanie Claudinot, Jun-Ichi Sakabe, Hideo Oshima, Christèle Gonneau, Thimios Mitsiadis, Daniel Littman, Paola Bonfanti, Geert Martens, Michael Nicolas, Ariane Rochat, Yann Barrandon
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/be9d6acf12fb439aa5de18cc8884d19d
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spelling	oai:doaj.org-article:be9d6acf12fb439aa5de18cc8884d19d2021-12-02T17:31:23ZTp63-expressing adult epithelial stem cells cross lineages boundaries revealing latent hairy skin competence10.1038/s41467-020-19485-32041-1723https://doaj.org/article/be9d6acf12fb439aa5de18cc8884d19d2020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19485-3https://doaj.org/toc/2041-1723Adult stem cells are thought to be fate restricted to lineages distinct to their tissue of origin. Here, the authors demonstrate that Tp63 expressing epithelial stem cells from several disparate tissues can respond to skin morphogenetic signals and contribute to hair follicles, sebaceous glands and/or epidermis.Stéphanie ClaudinotJun-Ichi SakabeHideo OshimaChristèle GonneauThimios MitsiadisDaniel LittmanPaola BonfantiGeert MartensMichael NicolasAriane RochatYann BarrandonNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Stéphanie Claudinot Jun-Ichi Sakabe Hideo Oshima Christèle Gonneau Thimios Mitsiadis Daniel Littman Paola Bonfanti Geert Martens Michael Nicolas Ariane Rochat Yann Barrandon Tp63-expressing adult epithelial stem cells cross lineages boundaries revealing latent hairy skin competence
description	Adult stem cells are thought to be fate restricted to lineages distinct to their tissue of origin. Here, the authors demonstrate that Tp63 expressing epithelial stem cells from several disparate tissues can respond to skin morphogenetic signals and contribute to hair follicles, sebaceous glands and/or epidermis.
format	article
author	Stéphanie Claudinot Jun-Ichi Sakabe Hideo Oshima Christèle Gonneau Thimios Mitsiadis Daniel Littman Paola Bonfanti Geert Martens Michael Nicolas Ariane Rochat Yann Barrandon
author_facet	Stéphanie Claudinot Jun-Ichi Sakabe Hideo Oshima Christèle Gonneau Thimios Mitsiadis Daniel Littman Paola Bonfanti Geert Martens Michael Nicolas Ariane Rochat Yann Barrandon
author_sort	Stéphanie Claudinot
title	Tp63-expressing adult epithelial stem cells cross lineages boundaries revealing latent hairy skin competence
title_short	Tp63-expressing adult epithelial stem cells cross lineages boundaries revealing latent hairy skin competence
title_full	Tp63-expressing adult epithelial stem cells cross lineages boundaries revealing latent hairy skin competence
title_fullStr	Tp63-expressing adult epithelial stem cells cross lineages boundaries revealing latent hairy skin competence
title_full_unstemmed	Tp63-expressing adult epithelial stem cells cross lineages boundaries revealing latent hairy skin competence
title_sort	tp63-expressing adult epithelial stem cells cross lineages boundaries revealing latent hairy skin competence
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/be9d6acf12fb439aa5de18cc8884d19d
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Tp63-expressing adult epithelial stem cells cross lineages boundaries revealing latent hairy skin competence

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