A biodegradable hybrid inorganic nanoscaffold for advanced stem cell therapy

The promise of stem cell therapy for treating central nervous system disease is limited by low stem cell transplantation survival rates and poorly controlled cell fate. Here, the authors develop a biodegradable nanoscaffold for spinal cord injury that enhances transplantation and differentiation of...

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Bibliographic Details
Main Authors: Letao Yang, Sy-Tsong Dean Chueng, Ying Li, Misaal Patel, Christopher Rathnam, Gangotri Dey, Lu Wang, Li Cai, Ki-Bum Lee
Format: article
Language:EN
Published: Nature Portfolio 2018
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Online Access:https://doaj.org/article/be9fc10d31f2457e96876bb1f1b4dff1
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Summary:The promise of stem cell therapy for treating central nervous system disease is limited by low stem cell transplantation survival rates and poorly controlled cell fate. Here, the authors develop a biodegradable nanoscaffold for spinal cord injury that enhances transplantation and differentiation of neural stem cells and delivers drugs.