A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages

Existing single-cell RNA-seq methods provide the transcriptome of a cellular phenotype at a single time point. Here, Kimmerlinget al. present a microfluidic platform that enables off-chip single-cell RNA-seq after multigenerational lineage tracking under controlled culture conditions.

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Autores principales:	Robert J. Kimmerling, Gregory Lee Szeto, Jennifer W. Li, Alex S. Genshaft, Samuel W. Kazer, Kristofor R. Payer, Jacob de Riba Borrajo, Paul C. Blainey, Darrell J. Irvine, Alex K. Shalek, Scott R. Manalis
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/bea614acf94645cdb3402d06fdfa86be
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spelling	oai:doaj.org-article:bea614acf94645cdb3402d06fdfa86be2021-12-02T16:57:49ZA microfluidic platform enabling single-cell RNA-seq of multigenerational lineages10.1038/ncomms102202041-1723https://doaj.org/article/bea614acf94645cdb3402d06fdfa86be2016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10220https://doaj.org/toc/2041-1723Existing single-cell RNA-seq methods provide the transcriptome of a cellular phenotype at a single time point. Here, Kimmerlinget al. present a microfluidic platform that enables off-chip single-cell RNA-seq after multigenerational lineage tracking under controlled culture conditions.Robert J. KimmerlingGregory Lee SzetoJennifer W. LiAlex S. GenshaftSamuel W. KazerKristofor R. PayerJacob de Riba BorrajoPaul C. BlaineyDarrell J. IrvineAlex K. ShalekScott R. ManalisNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Robert J. Kimmerling Gregory Lee Szeto Jennifer W. Li Alex S. Genshaft Samuel W. Kazer Kristofor R. Payer Jacob de Riba Borrajo Paul C. Blainey Darrell J. Irvine Alex K. Shalek Scott R. Manalis A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages
description	Existing single-cell RNA-seq methods provide the transcriptome of a cellular phenotype at a single time point. Here, Kimmerlinget al. present a microfluidic platform that enables off-chip single-cell RNA-seq after multigenerational lineage tracking under controlled culture conditions.
format	article
author	Robert J. Kimmerling Gregory Lee Szeto Jennifer W. Li Alex S. Genshaft Samuel W. Kazer Kristofor R. Payer Jacob de Riba Borrajo Paul C. Blainey Darrell J. Irvine Alex K. Shalek Scott R. Manalis
author_facet	Robert J. Kimmerling Gregory Lee Szeto Jennifer W. Li Alex S. Genshaft Samuel W. Kazer Kristofor R. Payer Jacob de Riba Borrajo Paul C. Blainey Darrell J. Irvine Alex K. Shalek Scott R. Manalis
author_sort	Robert J. Kimmerling
title	A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages
title_short	A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages
title_full	A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages
title_fullStr	A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages
title_full_unstemmed	A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages
title_sort	microfluidic platform enabling single-cell rna-seq of multigenerational lineages
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/bea614acf94645cdb3402d06fdfa86be
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A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages

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