A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages
Existing single-cell RNA-seq methods provide the transcriptome of a cellular phenotype at a single time point. Here, Kimmerlinget al. present a microfluidic platform that enables off-chip single-cell RNA-seq after multigenerational lineage tracking under controlled culture conditions.
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Nature Portfolio
2016
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oai:doaj.org-article:bea614acf94645cdb3402d06fdfa86be2021-12-02T16:57:49ZA microfluidic platform enabling single-cell RNA-seq of multigenerational lineages10.1038/ncomms102202041-1723https://doaj.org/article/bea614acf94645cdb3402d06fdfa86be2016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10220https://doaj.org/toc/2041-1723Existing single-cell RNA-seq methods provide the transcriptome of a cellular phenotype at a single time point. Here, Kimmerlinget al. present a microfluidic platform that enables off-chip single-cell RNA-seq after multigenerational lineage tracking under controlled culture conditions.Robert J. KimmerlingGregory Lee SzetoJennifer W. LiAlex S. GenshaftSamuel W. KazerKristofor R. PayerJacob de Riba BorrajoPaul C. BlaineyDarrell J. IrvineAlex K. ShalekScott R. ManalisNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-7 (2016) |
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Science Q |
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Science Q Robert J. Kimmerling Gregory Lee Szeto Jennifer W. Li Alex S. Genshaft Samuel W. Kazer Kristofor R. Payer Jacob de Riba Borrajo Paul C. Blainey Darrell J. Irvine Alex K. Shalek Scott R. Manalis A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages |
description |
Existing single-cell RNA-seq methods provide the transcriptome of a cellular phenotype at a single time point. Here, Kimmerlinget al. present a microfluidic platform that enables off-chip single-cell RNA-seq after multigenerational lineage tracking under controlled culture conditions. |
format |
article |
author |
Robert J. Kimmerling Gregory Lee Szeto Jennifer W. Li Alex S. Genshaft Samuel W. Kazer Kristofor R. Payer Jacob de Riba Borrajo Paul C. Blainey Darrell J. Irvine Alex K. Shalek Scott R. Manalis |
author_facet |
Robert J. Kimmerling Gregory Lee Szeto Jennifer W. Li Alex S. Genshaft Samuel W. Kazer Kristofor R. Payer Jacob de Riba Borrajo Paul C. Blainey Darrell J. Irvine Alex K. Shalek Scott R. Manalis |
author_sort |
Robert J. Kimmerling |
title |
A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages |
title_short |
A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages |
title_full |
A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages |
title_fullStr |
A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages |
title_full_unstemmed |
A microfluidic platform enabling single-cell RNA-seq of multigenerational lineages |
title_sort |
microfluidic platform enabling single-cell rna-seq of multigenerational lineages |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/bea614acf94645cdb3402d06fdfa86be |
work_keys_str_mv |
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